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Local Excitation, Global Inhibition Mechanism for Gradient Sensing: An Interactive Applet

Kutscher, B. ; Devreotes, P. ; Iglesias, P. A.

Science Signaling, 02/10/2004, Vol.2004(219), pp.pl3-pl3 [Peer Reviewed Journal]

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  • Title:
    Local Excitation, Global Inhibition Mechanism for Gradient Sensing: An Interactive Applet
  • Author: Kutscher, B. ; Devreotes, P. ; Iglesias, P. A.
  • Subjects: Anatomy & Physiology
  • Is Part Of: Science Signaling, 02/10/2004, Vol.2004(219), pp.pl3-pl3
  • Description: We have proposed a model in which cells detect gradients of chemoattractant by balancing a fast local excitation and a slower global inhibition. To illustrate this general mechanism, we have developed an interactive applet that mimics laboratory experiments in which either spatially homogeneous or heterogeneous stimuli of chemoattractant are applied.
  • Language: English
  • Identifier: ISSN: 1945-0877 ; E-ISSN: 1937-9145 ; DOI: http://dx.doi.org/10.1126/stke.2192004pl3
  • Source: American Association for the Advancement of Science (via CrossRef)

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