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Antimicrobial resistance and antibiotic consumption in Mexican hospitals

Miranda-Novales, María Guadalupe ; Flores-Moreno, Karen ; López-Vidal, Yolanda ; Rodríguez-Álvarez, Mauricio ; Solórzano-Santos, Fortino ; Soto-Hernández, José Luis ; Ponce de León-Rosales, Samuel ; Network, UNCAR

Salud pública de México, 2019-12-20, Vol.62 (1, ene-feb), p.42-49 [Peer Reviewed Journal]

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  • Title:
    Antimicrobial resistance and antibiotic consumption in Mexican hospitals
  • Author: Miranda-Novales, María Guadalupe ; Flores-Moreno, Karen ; López-Vidal, Yolanda ; Rodríguez-Álvarez, Mauricio ; Solórzano-Santos, Fortino ; Soto-Hernández, José Luis ; Ponce de León-Rosales, Samuel ; Network, UNCAR
  • Subjects: Index Medicus ; anti-bacterial agents ; drug resistance, microbial ; drug utilization
  • Is Part Of: Salud pública de México, 2019-12-20, Vol.62 (1, ene-feb), p.42-49
  • Description: To establish the current situation of antimicrobial resistance and antibiotic consumption in Mexican hospitals. Antimicrobial susceptibility data from blood and urine isolates were collected. Defined daily dose (DDD) of antibiotic consumption/100 occupied beds (OBD) was calculated. Study period: 2016 and 2017. Of 4 382 blood isolates, E. coli and K. pneumoniae were most frequently reported, with antimicrobial resistance >30% for most drugs tested, only for carbapenems and amikacin resistance were <20%. A. baumannii had antimicrobial resistance >20% to all drugs. Resistance to oxacillin in S. aureus was 20%. From 12 151 urine isolates, 90% corresponded to E. coli; resistance to ciprofloxacin, cephalosporins and trimethoprim/sulfamethoxazole was >50%, with good susceptibility to nitrofurantoin, amikacin and carbapenems. Global median antimicrobial consumption was 57.2 DDD/100 OB. s. This report shows a high antimicrobial resistance level in Gram-negative bacilli and provides an insight into the seriousness of the problem of antibiotic consumption.
  • Publisher: Mexico: Instituto Nacional de Salud Publica
  • Language: English
  • Identifier: ISSN: 1606-7916
    ISSN: 0036-3634
    EISSN: 1606-7916
    DOI: 10.21149/10543
    PMID: 31869560
  • Source: © ProQuest LLC All rights reserved

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