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Results 1 - 10 of 115  for Great Falls College MSU

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1
A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs
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A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs

Andrea E. Prota ; Katja Bargsten ; J. Fernando Diaz ; May Marsh ; Carmen Cuevas ; Marc Liniger ; Christian Neuhaus ; Jose M. Andreu ; Karl-Heinz Altmann ; Michel O. Steinmetz

Proceedings of the National Academy of Sciences - PNAS, 2014-08-11, Vol.111 (38), p.13817-13821

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2
Directed Hydrogenations and an Ireland-Claisen Rearrangement Linked to Evans-Tishchenko Chemistry: The Highly Efficient Total Synthesis of the Marine Cyclodepsipeptide Doliculide
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Directed Hydrogenations and an Ireland-Claisen Rearrangement Linked to Evans-Tishchenko Chemistry: The Highly Efficient Total Synthesis of the Marine Cyclodepsipeptide Doliculide

Chen, Tao ; Altmann, Karl-Heinz

Chemistry : a European journal, 2015-06-01, Vol.21 (23), p.8403-8407

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3
Multidimensional Design of Anticancer Peptides
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Multidimensional Design of Anticancer Peptides

Lin, Yen‐Chu ; Lim, Yi Fan ; Russo, Erica ; Schneider, Petra ; Bolliger, Lea ; Edenharter, Adriana ; Altmann, KarlHeinz ; Halin, Cornelia ; Hiss, Jan A ; Schneider, Gisbert

Angewandte Chemie (International ed.), 2015-08-24, Vol.54 (35), p.10370-10374 [Peer Reviewed Journal]

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4
Synthesis and Biological Activity of 7,8,9‐Trideoxy‐ and 7R DesTHP‐Peloruside A
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Synthesis and Biological Activity of 7,8,9‐Trideoxy‐ and 7R DesTHP‐Peloruside A

Wullschleger, Christoph W ; Gertsch, Jürg ; Altmann, KarlHeinz

Chemistry : a European journal, 2013-09-23, Vol.19 (39), p.13105-13111

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5
Structure-activity relationship studies on the macrolide exotoxin mycolactone of Mycobacterium ulcerans
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Structure-activity relationship studies on the macrolide exotoxin mycolactone of Mycobacterium ulcerans

Scherr, Nicole ; Gersbach, Philipp ; Dangy, Jean-Pierre ; Bomio, Claudio ; Li, Jun ; Altmann, Karl-Heinz ; Pluschke, Gerd Small, Pamela L. C

PLoS neglected tropical diseases, 2013, Vol.7 (3), p.e2143-e2143 [Peer Reviewed Journal]

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6
Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents
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Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents

Prota, Andrea E ; Bargsten, Katja ; Zurwerra, Didier ; Field, Jessica J ; Díaz, José Fernando ; Altmann, Karl-Heinz ; Steinmetz, Michel O

Science (American Association for the Advancement of Science), 2013-02-01, Vol.339 (6119), p.587-590 [Peer Reviewed Journal]

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7
Fragment‐Based De Novo Design Reveals a Small‐Molecule Inhibitor of Helicobacter Pylori HtrA
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Fragment‐Based De Novo Design Reveals a Small‐Molecule Inhibitor of Helicobacter Pylori HtrA

Perna, Anna M ; Rodrigues, Tiago ; Schmidt, Thomas P ; Böhm, Manja ; Stutz, Katharina ; Reker, Daniel ; Pfeiffer, Bernhard ; Altmann, KarlHeinz ; Backert, Steffen ; Wessler, Silja ; Schneider, Gisbert

Angewandte Chemie, 2015-08-24, Vol.127 (35), p.10382-10386 [Peer Reviewed Journal]

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8
Total Synthesis of the Tiacumicin B (Lipiarmycin A3/Fidaxomicin) Aglycone
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Total Synthesis of the Tiacumicin B (Lipiarmycin A3/Fidaxomicin) Aglycone

Glaus, Florian ; Altmann, Karl-Heinz

Angewandte Chemie (International ed.), 2015-02-02, Vol.54 (6), p.1937-1940 [Peer Reviewed Journal]

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9
Diversity through semisynthesis: the chemistry and biological activity of semisynthetic epothilone derivatives
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Diversity through semisynthesis: the chemistry and biological activity of semisynthetic epothilone derivatives

Altmann, Karl-Heinz ; Altmann, Karl-Heinz ; Gaugaz, Fabienne Z ; Gaugaz, Fabienne Z ; Schiess, Raphael ; Schiess, Raphael Appendino, Giovanni ; Appendino, Giovanni ; Banfi, Luca ; Banfi, Luca

Molecular diversity, 2011-05, Vol.15 (2), p.383-399 [Peer Reviewed Journal]

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10
High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cells
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High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cells

Pera, Benet ; Calvo-Vidal, M. Nieves ; Ambati, Srikanth ; Jordi, Michel ; Kahn, Alissa ; Díaz, J. Fernando ; Fang, Weishuo ; Altmann, Karl-Heinz ; Cerchietti, Leandro ; Moore, Malcolm A.S

Cancer Letters, 2015, Vol.368 (1), p.97-104 [Peer Reviewed Journal]

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