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Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation.

Sievers, Stuart A ; Karanicolas, John ; Chang, Howard W ; Zhao, Anni ; Jiang, Lin ; Zirafi, Onofrio ; Stevens, Jason T ; Münch, Jan ; Baker, David ; Eisenberg, David Sievers, Stuart A (correspondence author) ; Sievers, Stuart A (record owner)

Nature, June 15, 2011, Vol.475(7354), pp.96-100 [Peer Reviewed Journal]

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An Engineered Microbial Platform for Direct Biofuel Production from Brown Macroalgae

Wargacki, Adam ; Leonard, Effendi ; Win, Maung ; Regitsky, Drew ; Santos, Christine ; Kim, Peter ; Cooper, Susan ; Raisner, Ryan ; Herman, Asael ; Sivitz, Alicia ; Lakshmanaswamy, Arun ; Kashiyama, Yuki ; Baker, David ; Yoshikuni, Yasuo Wargacki, Adam (correspondence author)

Science (Washington), Jan 20, 2012, Vol.335(6066), pp.308-313 [Peer Reviewed Journal]

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Rational HIV immunogen design to target specific germline B cell receptors.

Jardine, Joseph ; Julien, Jean-Philippe ; Menis, Sergey ; Ota, Takayuki ; Kalyuzhniy, Oleksandr ; Mcguire, Andrew ; Sok, Devin ; Huang, Po-Ssu ; Macpherson, Skye ; Jones, Meaghan ; Nieusma, Travis ; Mathison, John ; Baker, David ; Ward, Andrew B ; Burton, Dennis R ; Stamatatos, Leonidas ; Nemazee, David ; Wilson, Ian A ; Schief, William R Jardine, Joseph (correspondence author) ; Jardine, Joseph (record owner)

Science (New York, N.Y.), May 10, 2013, Vol.340(6133), pp.711-716 [Peer Reviewed Journal]

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Improved molecular replacement by density- and energy-guided protein structure optimization.

Dimaio, Frank ; Terwilliger, Thomas C ; Read, Randy J ; Wlodawer, Alexander ; Oberdorfer, Gustav ; Wagner, Ulrike ; Valkov, Eugene ; Alon, Assaf ; Fass, Deborah ; Axelrod, Herbert L ; Das, Debanu ; Vorobiev, Sergey M ; Iwaï, Hideo ; Pokkuluri, P Raj ; Baker, David Dimaio, Frank (correspondence author) ; Dimaio, Frank (record owner)

Nature, May 26, 2011, Vol.473(7348), pp.540-543 [Peer Reviewed Journal]

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Computational design of proteins targeting the conserved stem region of influenza hemagglutinin.

Fleishman, Sarel J ; Whitehead, Timothy A ; Ekiert, Damian C ; Dreyfus, Cyrille ; Corn, Jacob E ; Strauch, Eva-Maria ; Wilson, Ian A ; Baker, David Fleishman, Sarel J (correspondence author) ; Fleishman, Sarel J (record owner)

Science (New York, N.Y.), May 13, 2011, Vol.332(6031), pp.816-821 [Peer Reviewed Journal]

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A synthetic homing endonuclease-based gene drive system in the human malaria mosquito.

Windbichler, Nikolai ; Menichelli, Miriam ; Papathanos, Philippos Aris ; Thyme, Summer B ; Li, Hui ; Ulge, Umut Y ; Hovde, Blake T ; Baker, David ; Monnat, Raymond J ; Burt, Austin ; Crisanti, Andrea Windbichler, Nikolai (correspondence author) ; Windbichler, Nikolai (record owner)

Nature, May 12, 2011, Vol.473(7346), pp.212-215 [Peer Reviewed Journal]

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Rational design of [Alpha]-helical tandem repeat proteins with closed architectures

Doyle, Lindsey ; Hallinan, Jazmine ; Bolduc, Jill ; Parmeggiani, Fabio ; Baker, David ; Stoddard, Barry ; Bradley, Philip

Nature, Dec 24-Dec 31, 2015, pp.585-588J [Peer Reviewed Journal]

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Proof of principle for epitope-focused vaccine design.

Correia, Bruno E ; Bates, John T ; Loomis, Rebecca J ; Baneyx, Gretchen ; Carrico, Chris ; Jardine, Joseph G ; Rupert, Peter ; Correnti, Colin ; Kalyuzhniy, Oleksandr ; Vittal, Vinayak ; Connell, Mary J ; Stevens, Eric ; Schroeter, Alexandria ; Chen, Man ; Macpherson, Skye ; Serra, Andreia M ; Adachi, Yumiko ; Holmes, Margaret A ; Li, Yuxing ; Klevit, Rachel E ; Graham, Barney S ; Wyatt, Richard T ; Baker, David ; Strong, Roland K ; Crowe, James E ; Johnson, Philip R ; Schief, William R Correia, Bruno E (correspondence author) ; Correia, Bruno E (record owner)

Nature, March 13, 2014, Vol.507(7491), pp.201-206 [Peer Reviewed Journal]

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Accurate design of co-assembling multi-component protein nanomaterials.

King, Neil P ; Bale, Jacob B ; Sheffler, William ; Mcnamara, Dan E ; Gonen, Shane ; Gonen, Tamir ; Yeates, Todd O ; Baker, David King, Neil P (correspondence author) ; King, Neil P (record owner)

Nature, June 5, 2014, Vol.510(7503), pp.103-108 [Peer Reviewed Journal]

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Exploring the repeat protein universe through computational protein design

Brunette, Tj ; Parmeggiani, Fabio ; Huang, Po-Ssu ; Bhabha, Gira ; Ekiert, Damian C ; Tsutakawa, Susan E ; Hura, Greg L ; Tainer, John A ; Baker, David

Nature, 2015, Vol.528(7583), p.580-584 [Peer Reviewed Journal]

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