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Mutations driving CLL and their evolution in progression and relapse.

Landau, Dan A ; Tausch, Eugen ; Taylor-Weiner, Amaro N ; Stewart, Chip ; Reiter, Johannes G ; Bahlo, Jasmin ; Kluth, Sandra ; Bozic, Ivana ; Lawrence, Mike ; Böttcher, Sebastian ; Carter, Scott L ; Cibulskis, Kristian ; Mertens, Daniel ; Sougnez, Carrie L ; Rosenberg, Mara ; Hess, Julian M ; Edelmann, Jennifer ; Kless, Sabrina ; Kneba, Michael ; Ritgen, Matthias ; Fink, Anna ; Fischer, Kirsten ; Gabriel, Stacey ; Lander, Eric S ; Nowak, Martin A ; Döhner, Hartmut ; Hallek, Michael ; Neuberg, Donna ; Getz, Gad ; Stilgenbauer, Stephan ; Wu, Catherine J Landau, Dan A (correspondence author) ; Landau, Dan A (record owner)

Nature, October 22, 2015, Vol.526(7574), pp.525-530 [Peer Reviewed Journal]

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Initial genome sequencing and analysis of multiple myeloma.

Chapman, Michael A ; Lawrence, Michael S ; Keats, Jonathan J ; Cibulskis, Kristian ; Sougnez, Carrie ; Schinzel, Anna C ; Harview, Christina L ; Brunet, Jean-Philippe ; Ahmann, Gregory J ; Adli, Mazhar ; Anderson, Kenneth C ; Ardlie, Kristin G ; Auclair, Daniel ; Baker, Angela ; Bergsagel, P Leif ; Bernstein, Bradley E ; Drier, Yotam ; Fonseca, Rafael ; Gabriel, Stacey B ; Hofmeister, Craig C ; Jagannath, Sundar ; Jakubowiak, Andrzej J ; Krishnan, Amrita ; Levy, Joan ; Liefeld, Ted ; Lonial, Sagar ; Mahan, Scott ; Mfuko, Bunmi ; Monti, Stefano ; Perkins, Louise M ; Onofrio, Robb ; Pugh, Trevor J ; Rajkumar, S Vincent ; Ramos, Alex H ; Siegel, David S ; Sivachenko, Andrey ; Stewart, A Keith ; Trudel, Suzanne ; Vij, Ravi ; Voet, Douglas ; Winckler, Wendy ; Zimmerman, Todd ; Carpten, John ; Trent, Jeff ; Hahn, William C ; Garraway, Levi A ; Meyerson, Matthew ; Lander, Eric S ; Getz, Gad ; Golub, Todd R Chapman, Michael A (correspondence author) ; Chapman, Michael A (record owner)

Nature, March 24, 2011, Vol.471(7339), pp.467-472 [Peer Reviewed Journal]

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Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

Lohr, Jens ; Stojanov, Petar ; Lawrence, Michael ; Auclair, Daniel ; Chapuy, Bjoern ; Sougnez, Carrie ; Cruz-Gordillo, Peter ; Knoechel, Birgit ; Asmann, Yan ; Slager, Susan ; Novak, Anne ; Dogan, Ahmet ; Ansell, Stephen ; Link, Brian ; Zou, Lihua ; Gould, Joshua ; Saksena, Gordon ; Stransky, Nicolas ; Rangel-Escareño, Claudia ; Fernandez-Lopez, Juan ; Hidalgo-Miranda, Alfredo ; Melendez-Zajgla, Jorge ; Hernández-Lemus, Enrique ; Y Celis, Angela ; Imaz-Rosshandler, Ivan ; Ojesina, Akinyemi ; Jung, Joonil ; Pedamallu, Chandra ; Lander, Eric ; Habermann, Thomas ; Cerhan, James ; Shipp, Margaret ; Getz, Gad ; Golub, Todd

Proceedings of the National Academy of Sciences of the United States of America, Mar 6, 2012, p.3879 [Peer Reviewed Journal]

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Comprehensive assessment of cancer missense mutation clustering in protein structures.

Kamburov, Atanas ; Lawrence, Michael S ; Polak, Paz ; Leshchiner, Ignaty ; Lage, Kasper ; Golub, Todd R ; Lander, Eric S ; Getz, Gad Kamburov, Atanas (correspondence author) ; Kamburov, Atanas (record owner)

Proceedings of the National Academy of Sciences of the United States of America, October 6, 2015, Vol.112(40), pp.E5486-E5495 [Peer Reviewed Journal]

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The mutational landscape of head and neck squamous cell carcinoma.

Stransky, Nicolas ; Egloff, Ann Marie ; Tward, Aaron D ; Kostic, Aleksandar D ; Cibulskis, Kristian ; Sivachenko, Andrey ; Kryukov, Gregory V ; Lawrence, Michael S ; Sougnez, Carrie ; Mckenna, Aaron ; Shefler, Erica ; Ramos, Alex H ; Stojanov, Petar ; Carter, Scott L ; Voet, Douglas ; Cortés, Maria L ; Auclair, Daniel ; Berger, Michael F ; Saksena, Gordon ; Guiducci, Candace ; Onofrio, Robert C ; Parkin, Melissa ; Romkes, Marjorie ; Weissfeld, Joel L ; Seethala, Raja R ; Wang, Lin ; Rangel-Escareño, Claudia ; Fernandez-Lopez, Juan Carlos ; Hidalgo-Miranda, Alfredo ; Melendez-Zajgla, Jorge ; Winckler, Wendy ; Ardlie, Kristin ; Gabriel, Stacey B ; Meyerson, Matthew ; Lander, Eric S ; Getz, Gad ; Golub, Todd R ; Garraway, Levi A ; Grandis, Jennifer R Stransky, Nicolas (correspondence author) ; Stransky, Nicolas (record owner)

Science (New York, N.Y.), August 26, 2011, Vol.333(6046), pp.1157-1160 [Peer Reviewed Journal]

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Comprehensive molecular characterization of human colon and rectal cancer.

Muzny, Donna M Bainbridge, Matthew N (record owner) ; Chang, Kyle ; Dinh, Huyen H ; Drummond, Jennifer A ; Fowler, Gerald ; Kovar, Christie L ; Lewis, Lora R ; Morgan, Margaret B ; Newsham, Irene F ; Reid, Jeffrey G ; Santibanez, Jireh ; Shinbrot, Eve ; Trevino, Lisa R ; Wu, Yuan-Qing ; Wang, Min ; Gunaratne, Preethi ; Donehower, Lawrence A ; Creighton, Chad J ; Wheeler, David A ; Gibbs, Richard A ; Lawrence, Michael S ; Voet, Douglas ; Jing, Rui ; Cibulskis, Kristian ; Sivachenko, Andrey ; Stojanov, Petar ; Mckenna, Aaron ; Lander, Eric S ; Gabriel, Stacey ; Getz, Gad ; Ding, Li ; Fulton, Robert S ; Koboldt, Daniel C ; Wylie, Todd ; Walker, Jason ; Dooling, David J ; Fulton, Lucinda ; Delehaunty, Kim D ; Fronick, Catrina C ; Demeter, Ryan ; Mardis, Elaine R ; Wilson, Richard K ; Chu, Andy ; Chun, Hye-Jung E ; Mungall, Andrew J ; Pleasance, Erin ; Robertson, A Gordon ; Stoll, Dominik ; Balasundaram, Miruna ; Birol, Inanc ; Butterfield, Yaron S N ; Chuah, Eric ; Coope, Robin J N ; Dhalla, Noreen ; Guin, Ranabir ; Hirst, Carrie ; Hirst, Martin ; Holt, Robert A ; Lee, Darlene ; Li, Haiyan I ; Mayo, Michael ; Moore, Richard A ; Schein, Jacqueline E ; Slobodan, Jared R ; Tam, Angela ; Thiessen, Nina ; Varhol, Richard ; Zeng, Thomas ; Zhao, Yongjun ; Jones, Steven J M ; Marra, Marco A ; Bass, Adam J ; Ramos, Alex H ; Saksena, Gordon ; Cherniack, Andrew D ; Schumacher, Stephen E ; Tabak, Barbara ; Carter, Scott L ; Pho, Nam H ; Nguyen, Huy ; Onofrio, Robert C ; Crenshaw, Andrew ; Ardlie, Kristin ; Beroukhim, Rameen ; Winckler, Wendy ; Getz, Gad ; Meyerson, Matthew ; Protopopov, Alexei ; Zhang, Juinhua ; Hadjipanayis, Angela ; Lee, Eunjung ; Xi, Ruibin ; Yang, Lixing ; Ren, Xiaojia ; Zhang, Hailei ; Sathiamoorthy, Narayanan ; Shukla, Sachet ; Chen, Peng-Chieh ; Haseley, Psalm ; Xiao, Yonghong ; Lee, Semin ; Seidman, Jonathan ; Chin, Lynda ; Park, Peter J ; Kucherlapati, Raju ; Auman, J Todd ; Hoadley, Katherine A ; Du, Ying ; Wilkerson, Matthew D ; Shi, Yan ; Liquori, Christina ; Meng, Shaowu ; Li, Ling ; Turman, Yidi J ; Topal, Michael D ; Tan, Donghui ; Waring, Scot ; Buda, Elizabeth ; Walsh, Jesse ; Jones, Corbin D ; Mieczkowski, Piotr A ; Singh, Darshan ; Wu, Junyuan ; Gulabani, Anisha ; Dolina, Peter ; Bodenheimer, Tom ; Hoyle, Alan P ; Simons, Janae V ; Soloway, Matthew ; Mose, Lisle E ; Jefferys, Stuart R ; Balu, Saianand ; O'Connor, Brian D ; Prins, Jan F ; Chiang, Derek Y ; Hayes, D Neil ; Perou, Charles M ; Hinoue, Toshinori ; Weisenberger, Daniel J ; Maglinte, Dennis T ; Pan, Fei ; Berman, Benjamin P ; Van Den Berg, David J ; Shen, Hui ; Triche, Timothy ; Baylin, Stephen B ; Laird, Peter W ; Getz, Gad ; Noble, Michael ; Voet, Doug ; Saksena, Gordon ; Gehlenborg, Nils ; Dicara, Daniel ; Zhang, Juinhua ; Zhang, Hailei ; Wu, Chang-Jiun ; Liu, Spring Yingchun ; Shukla, Sachet ; Lawrence, Michael S ; Zhou, Lihua ; Sivachenko, Andrey ; Lin, Pei ; Stojanov, Petar ; Jing, Rui ; Park, Richard W ; Nazaire, Marc-Danie ; Robinson, Jim ; Thorvaldsdottir, Helga ; Mesirov, Jill ; Park, Peter J ; Chin, Lynda ; Thorsson, Vesteinn ; Reynolds, Sheila M ; Bernard, Brady ; Kreisberg, Richard ; Lin, Jake ; Iype, Lisa ; Bressler, Ryan ; Erkkilä, Timo ; Gundapuneni, Madhumati ; Liu, Yuexin ; Norberg, Adam ; Robinson, Tom ; Yang, Da ; Zhang, Wei ; Shmulevich, Ilya ; de Ronde, Jorma J ; Schultz, Nikolaus ; Cerami, Ethan ; Ciriello, Giovanni ; Goldberg, Arthur P ; Gross, Benjamin ; Jacobsen, Anders ; Gao, Jianjiong ; Kaczkowski, Bogumil ; Sinha, Rileen ; Aksoy, B Arman ; Antipin, Yevgeniy ; Reva, Boris ; Shen, Ronglai ; Taylor, Barry S ; Chan, Timothy A ; Ladanyi, Marc ; Sander, Chris ; Akbani, Rehan ; Zhang, Nianxiang ; Broom, Bradley M ; Casasent, Tod ; Unruh, Anna ; Wakefield, Chris ; Hamilton, Stanley R ; Cason, R Craig ; Baggerly, Keith A ; Weinstein, John N ; Haussler, David ; Benz, Christopher C ; Stuart, Joshua M ; Benz, Stephen C ; Sanborn, J Zachary ; Vaske, Charles J ; Zhu, Jingchun ; Szeto, Christopher ; Scott, Gary K ; Yau, Christina ; Ng, Sam ; Goldstein, Ted ; Ellrott, Kyle ; Collisson, Eric ; Cozen, Aaron E ; Zerbino, Daniel ; Wilks, Christopher ; Craft, Brian ; Spellman, Paul ; Penny, Robert ; Shelton, Troy ; Hatfield, Martha ; Morris, Scott ; Yena, Peggy ; Shelton, Candace ; Sherman, Mark ; Paulauskis, Joseph ; Gastier-Foster, Julie M ; Bowen, Jay ; Ramirez, Nilsa C ; Black, Aaron ; Pyatt, Robert ; Wise, Lisa ; White, Peter ; Bertagnolli, Monica

Nature, July 18, 2012, Vol.487(7407), pp.330-337 [Peer Reviewed Journal]

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Characterizing genomic alterations in cancer by complementary functional associations.

Kim, Jong Wook ; Botvinnik, Olga B ; Abudayyeh, Omar ; Birger, Chet ; Rosenbluh, Joseph ; Shrestha, Yashaswi ; Abazeed, Mohamed E ; Hammerman, Peter S ; Dicara, Daniel ; Konieczkowski, David J ; Johannessen, Cory M ; Liberzon, Arthur ; Alizad-Rahvar, Amir Reza ; Alexe, Gabriela ; Aguirre, Andrew ; Ghandi, Mahmoud ; Greulich, Heidi ; Vazquez, Francisca ; Weir, Barbara A ; Van Allen, Eliezer M ; Tsherniak, Aviad ; Shao, Diane D ; Zack, Travis I ; Noble, Michael ; Getz, Gad ; Beroukhim, Rameen ; Garraway, Levi A ; Ardakani, Masoud ; Romualdi, Chiara ; Sales, Gabriele ; Barbie, David A ; Boehm, Jesse S ; Hahn, William C ; Mesirov, Jill P ; Tamayo, Pablo Kim, Jong Wook (correspondence author) ; Kim, Jong Wook (record owner)

Nature biotechnology, May 2016, Vol.34(5), pp.539-546 [Peer Reviewed Journal]

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Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2

Greulich, Heidi ; Kaplan, Bethany ; Mertins, Philipp ; Chen, Tzu-Hsiu ; Tanaka, Kumiko ; Yun, Cai-Hong ; Zhang, Xiaohong ; Lee, Se-Hoon ; Cho, Jeonghee ; Ambrogio, Lauren ; Liao, Rachel ; Imielinski, Marcin ; Banerji, Shantanu ; Berger, Alice ; Lawrence, Michael ; Zhang, Jinghui ; Pho, Nam ; Walker, Sarah ; Winckler, Wendy ; Getz, Gad ; Frank, David ; Hahn, William ; Eck, Michael ; Mani, D ; Jaffe, Jacob ; Carr, Steven ; Wong, Kwok-Kin ; Meyerson, Matthew

Proceedings of the National Academy of Sciences of the United States of America, Sep 4, 2012, p.14476 [Peer Reviewed Journal]

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Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.

Perry, Jennifer A ; Kiezun, Adam ; Tonzi, Peter ; Van Allen, Eliezer M ; Carter, Scott L ; Baca, Sylvan C ; Cowley, Glenn S ; Bhatt, Ami S ; Rheinbay, Esther ; Pedamallu, Chandra Sekhar ; Helman, Elena ; Taylor-Weiner, Amaro ; Mckenna, Aaron ; Deluca, David S ; Lawrence, Michael S ; Ambrogio, Lauren ; Sougnez, Carrie ; Sivachenko, Andrey ; Walensky, Loren D ; Wagle, Nikhil ; Mora, Jaume ; de Torres, Carmen ; Lavarino, Cinzia ; Dos Santos Aguiar, Simone ; Yunes, Jose Andres ; Brandalise, Silvia Regina ; Mercado-Celis, Gabriela Elisa ; Melendez-Zajgla, Jorge ; Cárdenas-Cardós, Rocío ; Velasco-Hidalgo, Liliana ; Roberts, Charles W M ; Garraway, Levi A ; Rodriguez-Galindo, Carlos ; Gabriel, Stacey B ; Lander, Eric S ; Golub, Todd R ; Orkin, Stuart H ; Getz, Gad ; Janeway, Katherine A Perry, Jennifer A (correspondence author) ; Perry, Jennifer A (record owner)

Proceedings of the National Academy of Sciences of the United States of America, December 23, 2014, Vol.111(51), pp.E5564-E5573 [Peer Reviewed Journal]

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Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing.

Lohr, Jens G ; Stojanov, Petar ; Lawrence, Michael S ; Auclair, Daniel ; Chapuy, Bjoern ; Sougnez, Carrie ; Cruz-Gordillo, Peter ; Knoechel, Birgit ; Asmann, Yan W ; Slager, Susan L ; Novak, Anne J ; Dogan, Ahmet ; Ansell, Stephen M ; Link, Brian K ; Zou, Lihua ; Gould, Joshua ; Saksena, Gordon ; Stransky, Nicolas ; Rangel-Escareño, Claudia ; Fernandez-Lopez, Juan Carlos ; Hidalgo-Miranda, Alfredo ; Melendez-Zajgla, Jorge ; Hernández-Lemus, Enrique ; Schwarz-Cruz Y Celis, Angela ; Imaz-Rosshandler, Ivan ; Ojesina, Akinyemi I ; Jung, Joonil ; Pedamallu, Chandra S ; Lander, Eric S ; Habermann, Thomas M ; Cerhan, James R ; Shipp, Margaret A ; Getz, Gad ; Golub, Todd R Lohr, Jens G (correspondence author) ; Lohr, Jens G (record owner)

Proceedings of the National Academy of Sciences of the United States of America, March 6, 2012, Vol.109(10), pp.3879-3884 [Peer Reviewed Journal]

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