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Mutations driving CLL and their evolution in progression and relapse.
Mutations driving CLL and their evolution in progression and relapse.
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Mutations driving CLL and their evolution in progression and relapse.

Landau, Dan A ; Tausch, Eugen ; Taylor-Weiner, Amaro N ; Stewart, Chip ; Reiter, Johannes G ; Bahlo, Jasmin ; Kluth, Sandra ; Bozic, Ivana ; Lawrence, Mike ; Böttcher, Sebastian ; Carter, Scott L ; Cibulskis, Kristian ; Mertens, Daniel ; Sougnez, Carrie L ; Rosenberg, Mara ; Hess, Julian M ; Edelmann, Jennifer ; Kless, Sabrina ; Kneba, Michael ; Ritgen, Matthias ; Fink, Anna ; Fischer, Kirsten ; Gabriel, Stacey ; Lander, Eric S ; Nowak, Martin A ; Döhner, Hartmut ; Hallek, Michael ; Neuberg, Donna ; Getz, Gad ; Stilgenbauer, Stephan ; Wu, Catherine J Landau, Dan A (correspondence author) ; Landau, Dan A (record owner)

Nature, October 22, 2015, Vol.526(7574), pp.525-530 [Peer Reviewed Journal]

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2
Initial genome sequencing and analysis of multiple myeloma.
Initial genome sequencing and analysis of multiple myeloma.
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Initial genome sequencing and analysis of multiple myeloma.

Chapman, Michael A ; Lawrence, Michael S ; Keats, Jonathan J ; Cibulskis, Kristian ; Sougnez, Carrie ; Schinzel, Anna C ; Harview, Christina L ; Brunet, Jean-Philippe ; Ahmann, Gregory J ; Adli, Mazhar ; Anderson, Kenneth C ; Ardlie, Kristin G ; Auclair, Daniel ; Baker, Angela ; Bergsagel, P Leif ; Bernstein, Bradley E ; Drier, Yotam ; Fonseca, Rafael ; Gabriel, Stacey B ; Hofmeister, Craig C ; Jagannath, Sundar ; Jakubowiak, Andrzej J ; Krishnan, Amrita ; Levy, Joan ; Liefeld, Ted ; Lonial, Sagar ; Mahan, Scott ; Mfuko, Bunmi ; Monti, Stefano ; Perkins, Louise M ; Onofrio, Robb ; Pugh, Trevor J ; Rajkumar, S Vincent ; Ramos, Alex H ; Siegel, David S ; Sivachenko, Andrey ; Stewart, A Keith ; Trudel, Suzanne ; Vij, Ravi ; Voet, Douglas ; Winckler, Wendy ; Zimmerman, Todd ; Carpten, John ; Trent, Jeff ; Hahn, William C ; Garraway, Levi A ; Meyerson, Matthew ; Lander, Eric S ; Getz, Gad ; Golub, Todd R Chapman, Michael A (correspondence author) ; Chapman, Michael A (record owner)

Nature, March 24, 2011, Vol.471(7339), pp.467-472 [Peer Reviewed Journal]

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3
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
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Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

Lohr, Jens ; Stojanov, Petar ; Lawrence, Michael ; Auclair, Daniel ; Chapuy, Bjoern ; Sougnez, Carrie ; Cruz-Gordillo, Peter ; Knoechel, Birgit ; Asmann, Yan ; Slager, Susan ; Novak, Anne ; Dogan, Ahmet ; Ansell, Stephen ; Link, Brian ; Zou, Lihua ; Gould, Joshua ; Saksena, Gordon ; Stransky, Nicolas ; Rangel-Escareño, Claudia ; Fernandez-Lopez, Juan ; Hidalgo-Miranda, Alfredo ; Melendez-Zajgla, Jorge ; Hernández-Lemus, Enrique ; Y Celis, Angela ; Imaz-Rosshandler, Ivan ; Ojesina, Akinyemi ; Jung, Joonil ; Pedamallu, Chandra ; Lander, Eric ; Habermann, Thomas ; Cerhan, James ; Shipp, Margaret ; Getz, Gad ; Golub, Todd

Proceedings of the National Academy of Sciences of the United States of America, Mar 6, 2012, p.3879 [Peer Reviewed Journal]

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4
Comprehensive assessment of cancer missense mutation clustering in protein structures.
Comprehensive assessment of cancer missense mutation clustering in protein structures.
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Comprehensive assessment of cancer missense mutation clustering in protein structures.

Kamburov, Atanas ; Lawrence, Michael S ; Polak, Paz ; Leshchiner, Ignaty ; Lage, Kasper ; Golub, Todd R ; Lander, Eric S ; Getz, Gad Kamburov, Atanas (correspondence author) ; Kamburov, Atanas (record owner)

Proceedings of the National Academy of Sciences of the United States of America, October 6, 2015, Vol.112(40), pp.E5486-E5495 [Peer Reviewed Journal]

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5
The mutational landscape of head and neck squamous cell carcinoma.
The mutational landscape of head and neck squamous cell carcinoma.
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The mutational landscape of head and neck squamous cell carcinoma.

Stransky, Nicolas ; Egloff, Ann Marie ; Tward, Aaron D ; Kostic, Aleksandar D ; Cibulskis, Kristian ; Sivachenko, Andrey ; Kryukov, Gregory V ; Lawrence, Michael S ; Sougnez, Carrie ; Mckenna, Aaron ; Shefler, Erica ; Ramos, Alex H ; Stojanov, Petar ; Carter, Scott L ; Voet, Douglas ; Cortés, Maria L ; Auclair, Daniel ; Berger, Michael F ; Saksena, Gordon ; Guiducci, Candace ; Onofrio, Robert C ; Parkin, Melissa ; Romkes, Marjorie ; Weissfeld, Joel L ; Seethala, Raja R ; Wang, Lin ; Rangel-Escareño, Claudia ; Fernandez-Lopez, Juan Carlos ; Hidalgo-Miranda, Alfredo ; Melendez-Zajgla, Jorge ; Winckler, Wendy ; Ardlie, Kristin ; Gabriel, Stacey B ; Meyerson, Matthew ; Lander, Eric S ; Getz, Gad ; Golub, Todd R ; Garraway, Levi A ; Grandis, Jennifer R Stransky, Nicolas (correspondence author) ; Stransky, Nicolas (record owner)

Science (New York, N.Y.), August 26, 2011, Vol.333(6046), pp.1157-1160 [Peer Reviewed Journal]

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6
Comprehensive molecular characterization of human colon and rectal cancer.
Comprehensive molecular characterization of human colon and rectal cancer.
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Comprehensive molecular characterization of human colon and rectal cancer.

Muzny, Donna M Bainbridge, Matthew N (record owner) ; Chang, Kyle ; Dinh, Huyen H ; Drummond, Jennifer A ; Fowler, Gerald ; Kovar, Christie L ; Lewis, Lora R ; Morgan, Margaret B ; Newsham, Irene F ; Reid, Jeffrey G ; Santibanez, Jireh ; Shinbrot, Eve ; Trevino, Lisa R ; Wu, Yuan-Qing ; Wang, Min ; Gunaratne, Preethi ; Donehower, Lawrence A ; Creighton, Chad J ; Wheeler, David A ; Gibbs, Richard A ; Lawrence, Michael S ; Voet, Douglas ; Jing, Rui ; Cibulskis, Kristian ; Sivachenko, Andrey ; Stojanov, Petar ; Mckenna, Aaron ; Lander, Eric S ; Gabriel, Stacey ; Getz, Gad ; Ding, Li ; Fulton, Robert S ; Koboldt, Daniel C ; Wylie, Todd ; Walker, Jason ; Dooling, David J ; Fulton, Lucinda ; Delehaunty, Kim D ; Fronick, Catrina C ; Demeter, Ryan ; Mardis, Elaine R ; Wilson, Richard K ; Chu, Andy ; Chun, Hye-Jung E ; Mungall, Andrew J ; Pleasance, Erin ; Robertson, A Gordon ; Stoll, Dominik ; Balasundaram, Miruna ; Birol, Inanc ; Butterfield, Yaron S N ; Chuah, Eric ; Coope, Robin J N ; Dhalla, Noreen ; Guin, Ranabir ; Hirst, Carrie ; Hirst, Martin ; Holt, Robert A ; Lee, Darlene ; Li, Haiyan I ; Mayo, Michael ; Moore, Richard A ; Schein, Jacqueline E ; Slobodan, Jared R ; Tam, Angela ; Thiessen, Nina ; Varhol, Richard ; Zeng, Thomas ; Zhao, Yongjun ; Jones, Steven J M ; Marra, Marco A ; Bass, Adam J ; Ramos, Alex H ; Saksena, Gordon ; Cherniack, Andrew D ; Schumacher, Stephen E ; Tabak, Barbara ; Carter, Scott L ; Pho, Nam H ; Nguyen, Huy ; Onofrio, Robert C ; Crenshaw, Andrew ; Ardlie, Kristin ; Beroukhim, Rameen ; Winckler, Wendy ; Getz, Gad ; Meyerson, Matthew ; Protopopov, Alexei ; Zhang, Juinhua ; Hadjipanayis, Angela ; Lee, Eunjung ; Xi, Ruibin ; Yang, Lixing ; Ren, Xiaojia ; Zhang, Hailei ; Sathiamoorthy, Narayanan ; Shukla, Sachet ; Chen, Peng-Chieh ; Haseley, Psalm ; Xiao, Yonghong ; Lee, Semin ; Seidman, Jonathan ; Chin, Lynda ; Park, Peter J ; Kucherlapati, Raju ; Auman, J Todd ; Hoadley, Katherine A ; Du, Ying ; Wilkerson, Matthew D ; Shi, Yan ; Liquori, Christina ; Meng, Shaowu ; Li, Ling ; Turman, Yidi J ; Topal, Michael D ; Tan, Donghui ; Waring, Scot ; Buda, Elizabeth ; Walsh, Jesse ; Jones, Corbin D ; Mieczkowski, Piotr A ; Singh, Darshan ; Wu, Junyuan ; Gulabani, Anisha ; Dolina, Peter ; Bodenheimer, Tom ; Hoyle, Alan P ; Simons, Janae V ; Soloway, Matthew ; Mose, Lisle E ; Jefferys, Stuart R ; Balu, Saianand ; O'Connor, Brian D ; Prins, Jan F ; Chiang, Derek Y ; Hayes, D Neil ; Perou, Charles M ; Hinoue, Toshinori ; Weisenberger, Daniel J ; Maglinte, Dennis T ; Pan, Fei ; Berman, Benjamin P ; Van Den Berg, David J ; Shen, Hui ; Triche, Timothy ; Baylin, Stephen B ; Laird, Peter W ; Getz, Gad ; Noble, Michael ; Voet, Doug ; Saksena, Gordon ; Gehlenborg, Nils ; Dicara, Daniel ; Zhang, Juinhua ; Zhang, Hailei ; Wu, Chang-Jiun ; Liu, Spring Yingchun ; Shukla, Sachet ; Lawrence, Michael S ; Zhou, Lihua ; Sivachenko, Andrey ; Lin, Pei ; Stojanov, Petar ; Jing, Rui ; Park, Richard W ; Nazaire, Marc-Danie ; Robinson, Jim ; Thorvaldsdottir, Helga ; Mesirov, Jill ; Park, Peter J ; Chin, Lynda ; Thorsson, Vesteinn ; Reynolds, Sheila M ; Bernard, Brady ; Kreisberg, Richard ; Lin, Jake ; Iype, Lisa ; Bressler, Ryan ; Erkkilä, Timo ; Gundapuneni, Madhumati ; Liu, Yuexin ; Norberg, Adam ; Robinson, Tom ; Yang, Da ; Zhang, Wei ; Shmulevich, Ilya ; de Ronde, Jorma J ; Schultz, Nikolaus ; Cerami, Ethan ; Ciriello, Giovanni ; Goldberg, Arthur P ; Gross, Benjamin ; Jacobsen, Anders ; Gao, Jianjiong ; Kaczkowski, Bogumil ; Sinha, Rileen ; Aksoy, B Arman ; Antipin, Yevgeniy ; Reva, Boris ; Shen, Ronglai ; Taylor, Barry S ; Chan, Timothy A ; Ladanyi, Marc ; Sander, Chris ; Akbani, Rehan ; Zhang, Nianxiang ; Broom, Bradley M ; Casasent, Tod ; Unruh, Anna ; Wakefield, Chris ; Hamilton, Stanley R ; Cason, R Craig ; Baggerly, Keith A ; Weinstein, John N ; Haussler, David ; Benz, Christopher C ; Stuart, Joshua M ; Benz, Stephen C ; Sanborn, J Zachary ; Vaske, Charles J ; Zhu, Jingchun ; Szeto, Christopher ; Scott, Gary K ; Yau, Christina ; Ng, Sam ; Goldstein, Ted ; Ellrott, Kyle ; Collisson, Eric ; Cozen, Aaron E ; Zerbino, Daniel ; Wilks, Christopher ; Craft, Brian ; Spellman, Paul ; Penny, Robert ; Shelton, Troy ; Hatfield, Martha ; Morris, Scott ; Yena, Peggy ; Shelton, Candace ; Sherman, Mark ; Paulauskis, Joseph ; Gastier-Foster, Julie M ; Bowen, Jay ; Ramirez, Nilsa C ; Black, Aaron ; Pyatt, Robert ; Wise, Lisa ; White, Peter ; Bertagnolli, Monica

Nature, July 18, 2012, Vol.487(7407), pp.330-337 [Peer Reviewed Journal]

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Characterizing genomic alterations in cancer by complementary functional associations.
Characterizing genomic alterations in cancer by complementary functional associations.
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Characterizing genomic alterations in cancer by complementary functional associations.

Kim, Jong Wook ; Botvinnik, Olga B ; Abudayyeh, Omar ; Birger, Chet ; Rosenbluh, Joseph ; Shrestha, Yashaswi ; Abazeed, Mohamed E ; Hammerman, Peter S ; Dicara, Daniel ; Konieczkowski, David J ; Johannessen, Cory M ; Liberzon, Arthur ; Alizad-Rahvar, Amir Reza ; Alexe, Gabriela ; Aguirre, Andrew ; Ghandi, Mahmoud ; Greulich, Heidi ; Vazquez, Francisca ; Weir, Barbara A ; Van Allen, Eliezer M ; Tsherniak, Aviad ; Shao, Diane D ; Zack, Travis I ; Noble, Michael ; Getz, Gad ; Beroukhim, Rameen ; Garraway, Levi A ; Ardakani, Masoud ; Romualdi, Chiara ; Sales, Gabriele ; Barbie, David A ; Boehm, Jesse S ; Hahn, William C ; Mesirov, Jill P ; Tamayo, Pablo Kim, Jong Wook (correspondence author) ; Kim, Jong Wook (record owner)

Nature biotechnology, May 2016, Vol.34(5), pp.539-546 [Peer Reviewed Journal]

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8
Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2
Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2
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Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2

Greulich, Heidi ; Kaplan, Bethany ; Mertins, Philipp ; Chen, Tzu-Hsiu ; Tanaka, Kumiko ; Yun, Cai-Hong ; Zhang, Xiaohong ; Lee, Se-Hoon ; Cho, Jeonghee ; Ambrogio, Lauren ; Liao, Rachel ; Imielinski, Marcin ; Banerji, Shantanu ; Berger, Alice ; Lawrence, Michael ; Zhang, Jinghui ; Pho, Nam ; Walker, Sarah ; Winckler, Wendy ; Getz, Gad ; Frank, David ; Hahn, William ; Eck, Michael ; Mani, D ; Jaffe, Jacob ; Carr, Steven ; Wong, Kwok-Kin ; Meyerson, Matthew

Proceedings of the National Academy of Sciences of the United States of America, Sep 4, 2012, p.14476 [Peer Reviewed Journal]

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9
Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.
Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.
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Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.

Perry, Jennifer A ; Kiezun, Adam ; Tonzi, Peter ; Van Allen, Eliezer M ; Carter, Scott L ; Baca, Sylvan C ; Cowley, Glenn S ; Bhatt, Ami S ; Rheinbay, Esther ; Pedamallu, Chandra Sekhar ; Helman, Elena ; Taylor-Weiner, Amaro ; Mckenna, Aaron ; Deluca, David S ; Lawrence, Michael S ; Ambrogio, Lauren ; Sougnez, Carrie ; Sivachenko, Andrey ; Walensky, Loren D ; Wagle, Nikhil ; Mora, Jaume ; de Torres, Carmen ; Lavarino, Cinzia ; Dos Santos Aguiar, Simone ; Yunes, Jose Andres ; Brandalise, Silvia Regina ; Mercado-Celis, Gabriela Elisa ; Melendez-Zajgla, Jorge ; Cárdenas-Cardós, Rocío ; Velasco-Hidalgo, Liliana ; Roberts, Charles W M ; Garraway, Levi A ; Rodriguez-Galindo, Carlos ; Gabriel, Stacey B ; Lander, Eric S ; Golub, Todd R ; Orkin, Stuart H ; Getz, Gad ; Janeway, Katherine A Perry, Jennifer A (correspondence author) ; Perry, Jennifer A (record owner)

Proceedings of the National Academy of Sciences of the United States of America, December 23, 2014, Vol.111(51), pp.E5564-E5573 [Peer Reviewed Journal]

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10
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing.
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing.
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Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing.

Lohr, Jens G ; Stojanov, Petar ; Lawrence, Michael S ; Auclair, Daniel ; Chapuy, Bjoern ; Sougnez, Carrie ; Cruz-Gordillo, Peter ; Knoechel, Birgit ; Asmann, Yan W ; Slager, Susan L ; Novak, Anne J ; Dogan, Ahmet ; Ansell, Stephen M ; Link, Brian K ; Zou, Lihua ; Gould, Joshua ; Saksena, Gordon ; Stransky, Nicolas ; Rangel-Escareño, Claudia ; Fernandez-Lopez, Juan Carlos ; Hidalgo-Miranda, Alfredo ; Melendez-Zajgla, Jorge ; Hernández-Lemus, Enrique ; Schwarz-Cruz Y Celis, Angela ; Imaz-Rosshandler, Ivan ; Ojesina, Akinyemi I ; Jung, Joonil ; Pedamallu, Chandra S ; Lander, Eric S ; Habermann, Thomas M ; Cerhan, James R ; Shipp, Margaret A ; Getz, Gad ; Golub, Todd R Lohr, Jens G (correspondence author) ; Lohr, Jens G (record owner)

Proceedings of the National Academy of Sciences of the United States of America, March 6, 2012, Vol.109(10), pp.3879-3884 [Peer Reviewed Journal]

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