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Ebf2 is a selective marker of brown and beige adipogenic precursor cells.

Wang, Wenshan ; Kissig, Megan ; Rajakumari, Sona ; Huang, Li ; Lim, Hee-Woong ; Won, Kyoung-Jae ; Seale, Patrick Wang, Wenshan (correspondence author) ; Wang, Wenshan (record owner)

Proceedings of the National Academy of Sciences of the United States of America, October 7, 2014, Vol.111(40), pp.14466-14471 [Peer Reviewed Journal]

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Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge

Matthew J. Emmett ; Hee-Woong Lim ; Jennifer Jager ; Hannah J. Richter ; Marine Adlanmerini ; Lindsey C. Peed ; Erika R. Briggs ; David J. Steger ; Tao Ma ; Carrie A. Sims ; Joseph A. Baur ; Liming Pei ; Kyoung-Jae Won ; Patrick Seale ; Zachary Gerhart-Hines ; Mitchell A. Lazar

Nature, 2017 [Peer Reviewed Journal]

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PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing

Kissig, Megan ; Ishibashi, Jeff ; Harms, Matthew J ; Lim, Hee‐Woong ; Stine, Rachel R ; Won, Kyoung‐Jae ; Seale, Patrick

EMBO Journal, 01 June 2017, Vol.36(11), pp.1528-1542 [Peer Reviewed Journal]

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EBF2 Determines and Maintains Brown Adipocyte Identity

Rajakumari, Sona ; Wu, Jun ; Ishibashi, Jeff ; Lim, Hee-Woong ; Giang, An-Hoa ; Won, Kyoung-Jae ; Reed, Randall r ; Seale, Patrick

Cell Metabolism, 02 April 2013, Vol.17(4), pp.562-574 [Peer Reviewed Journal]

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Targeting PPARγ in the epigenome rescues genetic metabolic defects in mice.

Soccio, Raymond E ; Li, Zhenghui ; Chen, Eric R ; Foong, Yee Hoon ; Benson, Kiara K ; Dispirito, Joanna R ; Mullican, Shannon E ; Emmett, Matthew J ; Briggs, Erika R ; Peed, Lindsey C ; Dzeng, Richard K ; Medina, Carlos J ; Jolivert, Jennifer F ; Kissig, Megan ; Rajapurkar, Satyajit R ; Damle, Manashree ; Lim, Hee-Woong ; Won, Kyoung-Jae ; Seale, Patrick ; Steger, David J ; Lazar, Mitchell A Soccio, Raymond E (correspondence author) ; Soccio, Raymond E (record owner)

The Journal of clinical investigation, April 3, 2017, Vol.127(4), pp.1451-1462 [Peer Reviewed Journal]

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EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex.

Shapira, Suzanne N ; Lim, Hee-Woong ; Rajakumari, Sona ; Sakers, Alexander P ; Ishibashi, Jeff ; Harms, Matthew J ; Won, Kyoung-Jae ; Seale, Patrick Shapira, Suzanne N (correspondence author) ; Shapira, Suzanne N (record owner)

Genes & development, April 1, 2017, Vol.31(7), pp.660-673 [Peer Reviewed Journal]

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Prdm16 Is Required for the Maintenance of Brown Adipocyte Identity and Function in Adult Mice

Harms, Matthew j ; Ishibashi, Jeff ; Wang, Wenshan ; Lim, Hee-Woong ; Goyama, Susumu ; Sato, Tomohiko ; Kurokawa, Mineo ; Won, Kyoung-Jae ; Seale, Patrick

Cell Metabolism, 01 April 2014, Vol.19(4), pp.593-604 [Peer Reviewed Journal]

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PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program

Harms, Matthew J ; Lim, Hee-Woong ; Ho, Yugong ; Shapira, Suzanne N ; Ishibashi, Jeff ; Rajakumari, Sona ; Steger, David J ; Lazar, Mitchell A ; Won, Kyoung-Jae ; Seale, Patrick

Genes & development, 01 February 2015, Vol.29(3), pp.298-307 [Peer Reviewed Journal]

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  1. Won, Kyoung-Jae
  2. Seale, Patrick
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  4. Lim, Hee-Woong
  5. Won, Kj

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