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Microfluidics: Exploiting elephants in the room.

Wootton, Robert C R ; Demello, Andrew J Wootton, Robert C R (correspondence author) ; Wootton, Robert C R (record owner)

Nature, April 8, 2010, Vol.464(7290), pp.839-840 [Peer Reviewed Journal]

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Traditional drug-discovery model ripe for reform: academic researchers set to play much greater role in pharmaceutical development.(PHARMACEUTICALS)

Cressey, Daniel

Nature, March 3, 2011, Vol.471(7336), p.17(2) [Peer Reviewed Journal]

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The learning curve: researchers say that some chemicals have unexpected and potent effects at very low doses--but regulators aren't convinced.(NEWS)

Fagin, Dan

Nature, Oct 25, 2012, Vol.490(7421), p.462(4) [Peer Reviewed Journal]

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Chemical con artists foil drug discovery: naivety about promiscuous, assay-duping molecules is polluting the literature and wasting resources, warn Jonathan Baell and Michael A. Walters.(COMMENT)(pan-assay interference compounds)

Baell, Jonathan ; Walters, Michael A.

Nature, Sept 25, 2014, Vol.513(7519), p.481(3) [Peer Reviewed Journal]

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Analog-to-digital drug screening: current methods for screening libraries of compounds for biological activity are rather cumbersome, slow and imprecise. A method that breaks up a continuous flow of a compound's solution into droplets offers radical improvements.(MICROFLUIDICS)

Wootton, Robert C.R. ; Demello, Andrew J.

Nature, March 1, 2012, Vol.483(7387), p.43(2) [Peer Reviewed Journal]

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Silencing psoriasis: the latest drugs hold fantastic promise for people with severe psoriasis. But where are the treatment options for the far larger number with less serious cases?(THERAPEUTICS)

Crow, James Mitchell

Nature, Dec 20, 2012, Vol.492(7429), p.S58(2) [Peer Reviewed Journal]

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Addendum: The cancer cell line encyclopedia enables predictive modelling of anticancer drug sensitivity.(ADDENDUM)

Barretina, J ; Caponigro, G ; Stransky, N ; Venkatesan, K ; Margolin, AA ; Kim, S ; Wilson, CJ ; Lehar, J ; Kryukov, Gv ; Sonkin, D ; Reddy, A ; Liu, M ; Murray, L ; Berger, Mf ; Monahan, Je ; Morais, P ; Meltzer, J ; Korejwa, A ; Jane-Valbuena, J ; Mapa, FA ; Thibault, J ; Bric-Furlong, E ; Raman, P ; Shipway, A ; Engels, Ih ; Cheng, J ; Yu, Gk ; Yu, Jj ; Aspesi, P ; de Silva, M ; Jagtap, K ; Jones, MD ; Wang, L ; Hatton, C ; Palescandolo, E ; Gupta, S ; Mahan, S ; Sougnez, C ; Onofrio, RC ; Liefeld, T ; Macconaill, L ; Winckler, W ; Reich, M ; Li, Nx ; Mesirov, JP ; Gabriel, SB ; Getz, G ; Ardlie, K ; Chan, V ; Myer, Ve ; Weber, Bl ; Porter, J ; Warmuth, M ; Finan, P ; Harris, Jl ; Meyerson, M ; Golub, Tr ; Morrissey, MP ; Sellers, Wr ; Schlegel, R ; Garraway, La;

Nature, Dec 13, 2012, Vol.492(7428), p.290(1) [Peer Reviewed Journal]

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'Master protocol' aims to revamp cancer trials: pilot project will bring drug companies together to test targeted lung-cancer therapies.(PERSONALIZED MEDICINE)

Ledford, Heidi

Nature, June 13, 2013, Vol.498(7453), p.146(2) [Peer Reviewed Journal]

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Automated design of ligands to polypharmacological profiles.(RESEARCH: ARTICLE)(Report)

Besnard, Jeremy ; Ruda, Gian Filippo ; Setola, Vincent ; Abecassis, Keren ; Rodriguiz, Ramona M. ; Huang, Xi-Ping ; Norval, Suzanne ; Sassano, Maria F. ; Shin, Antony I. ; Webster, Lauren A. ; Simeons, Frederick R.C. ; Stojanovski, Laste ; Prat, Annik ; Seidah, Nabil G. ; Constam, Daniel B. ; Bickerton, G. Richard ; Read, Kevin D. ; Wetsel, William C. ; Gilbert, Ian H. ; Roth, Bryan L. ; Hopkins, Andrew L.

Nature, Dec 13, 2012, Vol.492(7428), p.215(8) [Peer Reviewed Journal]

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Testing time for stem cells.

Baker, Monya Baker, Monya (correspondence author) ; Baker, Monya (record owner)

Nature, February 11, 2010, Vol.463(7282), p.719 [Peer Reviewed Journal]

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