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Serendipitous Discovery of a Potent Influenza Virus A Neuraminidase Inhibitor

Mohan, Sankar ; Kerry, Philip S. ; Bance, Nicole ; Niikura, Masahiro ; Pinto, B. Mario

Angewandte Chemie, 20 January 2014, Vol.126(4), pp.1094-1098 [Peer Reviewed Journal]

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Stabilizer‐Guided Inhibition of Protein–Protein Interactions

Milroy, Lech‐Gustav ; Bartel, Maria ; Henen, Morkos A. ; Leysen, Seppe ; Adriaans, Joris M. C. ; Brunsveld, Luc ; Landrieu, Isabelle ; Ottmann, Christian

Angewandte Chemie, 21 December 2015, Vol.127(52), pp.15946-15950 [Peer Reviewed Journal]

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Synthesis of a Natural Product‐Like Compound Collection through Oxidative Cleavage and Cyclization of Linear Peptides

Petersen, Rico ; Le Quement, Sebastian T. ; Nielsen, Thomas E.

Angewandte Chemie, 27 October 2014, Vol.126(44), pp.11972-11976 [Peer Reviewed Journal]

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Discovery, Structure Elucidation, and Biological Characterization of Nannocystin A, a Macrocyclic Myxobacterial Metabolite with Potent Antiproliferative Properties

Hoffmann, Holger ; Kogler, Herbert ; Heyse, Winfried ; Matter, Hans ; Caspers, Michael ; Schummer, Dietmar ; Klemke‐Jahn, Christine ; Bauer, Armin ; Penarier, Geraldine ; Debussche, Laurent ; Brönstrup, Mark

Angewandte Chemie, 24 August 2015, Vol.127(35), pp.10283-10286 [Peer Reviewed Journal]

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Overcoming the Unexpected Functional Inversion of a PqsR Antagonist in Pseudomonas aeruginosa: An In Vivo Potent Antivirulence Agent Targeting pqs Quorum Sensing

Lu, Cenbin ; Maurer, Christine K. ; Kirsch, Benjamin ; Steinbach, Anke ; Hartmann, Rolf W.

Angewandte Chemie, 20 January 2014, Vol.126(4), pp.1127-1130 [Peer Reviewed Journal]

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Structure‐Based Approach To Improve a Small‐Molecule Inhibitor by the Use of a Competitive Peptide Ligand

Ono, Katsuki ; Takeuchi, Koh ; Ueda, Hiroshi ; Morita, Yasuhiro ; Tanimura, Ryuji ; Shimada, Ichio ; Takahashi, Hideo

Angewandte Chemie, 03 March 2014, Vol.126(10), pp.2635-2639 [Peer Reviewed Journal]

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Crowdsourcing Natural Products Discovery to Access Uncharted Dimensions of Fungal Metabolite Diversity

Du, Lin ; Robles, Andrew J. ; King, Jarrod B. ; Powell, Douglas R. ; Miller, Andrew N. ; Mooberry, Susan L. ; Cichewicz, Robert H.

Angewandte Chemie, 13 January 2014, Vol.126(3), pp.823-828 [Peer Reviewed Journal]

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Multitarget Drug Discovery for Alzheimer's Disease: Triazinones as BACE‐1 and GSK‐3β Inhibitors

Prati, Federica ; De Simone, Angela ; Bisignano, Paola ; Armirotti, Andrea ; Summa, Maria ; Pizzirani, Daniela ; Scarpelli, Rita ; Perez, Daniel I. ; Andrisano, Vincenza ; Perez‐Castillo, Ana ; Monti, Barbara ; Massenzio, Francesca ; Polito, Letizia ; Racchi, Marco ; Favia, Angelo D. ; Bottegoni, Giovanni ; Martinez, Ana ; Bolognesi, Maria Laura ; Cavalli, Andrea

Angewandte Chemie, 26 January 2015, Vol.127(5), pp.1598-1602 [Peer Reviewed Journal]

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Structural Basis of Microtubule Stabilization by Laulimalide and Peloruside A

Prota, Andrea E. ; Bargsten, Katja ; Northcote, Peter T. ; Marsh, May ; Altmann, Karl‐Heinz ; Miller, John H. ; Díaz, José Fernando ; Steinmetz, Michel O.

Angewandte Chemie, 03 February 2014, Vol.126(6), pp.1647-1651 [Peer Reviewed Journal]

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Autocrine‐Based Selection of Drugs That Target Ion Channels from Combinatorial Venom Peptide Libraries

Zhang, Hongkai ; Du, Mingjuan ; Xie, Jia ; Liu, Xiao ; Sun, Jingying ; Wang, Wei ; Xin, Xiu ; Possani, Lourival D. ; Yea, Kyungmoo ; Lerner, Richard A.

Angewandte Chemie, 01 August 2016, Vol.128(32), pp.9452-9456 [Peer Reviewed Journal]

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