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MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis.

Anand, Sudarshan ; Majeti, Bharat K ; Acevedo, Lisette M ; Murphy, Eric A ; Mukthavaram, Rajesh ; Scheppke, Lea ; Huang, Miller ; Shields, David J ; Lindquist, Jeffrey N ; Lapinski, Philip E ; King, Philip D ; Weis, Sara M ; Cheresh, David A Anand, Sudarshan (correspondence author) ; Anand, Sudarshan (record owner)

Nature medicine, August 2010, Vol.16(8), pp.909-914 [Peer Reviewed Journal]

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Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids

Huang, Ling ; Holtzinger, Audrey ; Jagan, Ishaan ; Begora, Michael ; Lohse, Ines ; Ngai, Nicholas ; Nostro, Cristina ; Wang, Rennian ; Muthuswamy, Lakshmi B ; Crawford, Howard C ; Arrowsmith, Cheryl ; Kalloger, Steve E ; Renouf, Daniel J ; Connor, Ashton A ; Cleary, Sean ; Schaeffer, David F ; Roehrl, Michael ; Tsao, Ming-Sound ; Gallinger, Steven ; Keller, Gordon ; Muthuswamy, Senthil K

Nature Medicine, 2015, Vol.21(11), p.1364(8) [Peer Reviewed Journal]

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Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis.

Pethe, Kevin ; Bifani, Pablo ; Jang, Jichan ; Kang, Sunhee ; Park, Seijin ; Ahn, Sujin ; Jiricek, Jan ; Jung, Juyoung ; Jeon, Hee Kyoung ; Cechetto, Jonathan ; Christophe, Thierry ; Lee, Honggun ; Kempf, Marie ; Jackson, Mary ; Lenaerts, Anne J ; Pham, Ha ; Jones, Victoria ; Seo, Min Jung ; Kim, Young Mi ; Seo, Mooyoung ; Seo, Jeong Jea ; Park, Dongsik ; Ko, Yoonae ; Choi, Inhee ; Kim, Ryangyeo ; Kim, Se Yeon ; Lim, Seungbin ; Yim, Seung-Ae ; Nam, Jiyoun ; Kang, Hwankyu ; Kwon, Haejin ; Oh, Chun-Taek ; Cho, Yoojin ; Jang, Yunhee ; Kim, Junghwan ; Chua, Adeline ; Tan, Bee Huat ; Nanjundappa, Mahesh B ; Rao, Srinivasa P S ; Barnes, Whitney S ; Wintjens, René ; Walker, John R ; Alonso, Sylvie ; Lee, Saeyeon ; Kim, Jungjun ; Oh, Soohyun ; Oh, Taegwon ; Nehrbass, Ulf ; Han, Sung-Jun ; No, Zaesung ; Lee, Jinhwa ; Brodin, Priscille ; Cho, Sang-Nae ; Nam, Kiyean ; Kim, Jaeseung Pethe, Kevin (correspondence author) ; Pethe, Kevin (record owner)

Nature medicine, September 2013, Vol.19(9), pp.1157-1160 [Peer Reviewed Journal]

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A high-throughput drug screen for Entamoeba histolytica identifies a new lead and target.

Debnath, Anjan ; Parsonage, Derek ; Andrade, Rosa M ; He, Chen ; Cobo, Eduardo R ; Hirata, Ken ; Chen, Steven ; García-Rivera, Guillermina ; Orozco, Esther ; Martínez, Máximo B ; Gunatilleke, Shamila S ; Barrios, Amy M ; Arkin, Michelle R ; Poole, Leslie B ; Mckerrow, James H ; Reed, Sharon L Debnath, Anjan (correspondence author) ; Debnath, Anjan (record owner)

Nature medicine, June 2012, Vol.18(6), pp.956-960 [Peer Reviewed Journal]

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Roadblocks to translational challenges on viral pathogenesis.

Deeks, Steven ; Drosten, Christian ; Picker, Louis ; Subbarao, Kanta ; Suzich, Joann Deeks, Steven (correspondence author) ; Deeks, Steven (record owner)

Nature medicine, January 2013, Vol.19(1), pp.30-34 [Peer Reviewed Journal]

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Ammonia triggers neuronal disinhibition and seizures by impairing astrocyte potassium buffering.

Rangroo Thrane, Vinita ; Thrane, Alexander S ; Wang, Fushun ; Cotrina, Maria L ; Smith, Nathan A ; Chen, Michael ; Xu, Qiwu ; Kang, Ning ; Fujita, Takumi ; Nagelhus, Erlend A ; Nedergaard, Maiken Rangroo Thrane, Vinita (correspondence author) ; Rangroo Thrane, Vinita (record owner)

Nature medicine, December 2013, Vol.19(12), pp.1643-1648 [Peer Reviewed Journal]

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Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs.

Henderson, Neil C ; Arnold, Thomas D ; Katamura, Yoshio ; Giacomini, Marilyn M ; Rodriguez, Juan D ; Mccarty, Joseph H ; Pellicoro, Antonella ; Raschperger, Elisabeth ; Betsholtz, Christer ; Ruminski, Peter G ; Griggs, David W ; Prinsen, Michael J ; Maher, Jacquelyn J ; Iredale, John P ; Lacy-Hulbert, Adam ; Adams, Ralf H ; Sheppard, Dean Henderson, Neil C (correspondence author) ; Henderson, Neil C (record owner)

Nature medicine, December 2013, Vol.19(12), pp.1617-1624 [Peer Reviewed Journal]

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Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis.

Mei, Feng ; Fancy, Stephen P J ; Shen, Yun-An A ; Niu, Jianqin ; Zhao, Chao ; Presley, Bryan ; Miao, Edna ; Lee, Seonok ; Mayoral, Sonia R ; Redmond, Stephanie A ; Etxeberria, Ainhoa ; Xiao, Lan ; Franklin, Robin J M ; Green, Ari ; Hauser, Stephen L ; Chan, Jonah R Mei, Feng (correspondence author) ; Mei, Feng (record owner)

Nature medicine, August 2014, Vol.20(8), pp.954-960 [Peer Reviewed Journal]

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Combined treatment with oral metronidazole and N-acetylcysteine is effective in ethylmalonic encephalopathy.

Viscomi, Carlo ; Burlina, Alberto B ; Dweikat, Imad ; Savoiardo, Mario ; Lamperti, Costanza ; Hildebrandt, Tatjana ; Tiranti, Valeria ; Zeviani, Massimo Viscomi, Carlo (correspondence author) ; Viscomi, Carlo (record owner)

Nature medicine, August 2010, Vol.16(8), pp.869-871 [Peer Reviewed Journal]

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'Emancipated' biotechs offer new drugs for neurodegeneration

Basu, Paroma

Nature Medicine, Aug 2003, p.981 [Peer Reviewed Journal]

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