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1
Integrating high-content screening and ligand-target prediction to identify mechanism of action
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Integrating high-content screening and ligand-target prediction to identify mechanism of action

Young, Daniel W ; Bender, Andreas ; Hoyt, Jonathan ; McWhinnie, Elizabeth ; Chirn, Gung-Wei ; Tao, Charles Y ; Tallarico, John A ; Labow, Mark ; Jenkins, Jeremy L ; Mitchison, Timothy J ; Feng, Yan

Nature chemical biology, 2007-12-09, Vol.4 (1), p.59-68 [Peer Reviewed Journal]

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2
Synthesis and characterization of novel 2-amino-chromene-nitriles that target Bcl-2 in acute myeloid leukemia cell lines
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Synthesis and characterization of novel 2-amino-chromene-nitriles that target Bcl-2 in acute myeloid leukemia cell lines

Keerthy, Hosadurga K ; Garg, Manoj ; Mohan, Chakrabhavi D ; Madan, Vikas ; Kanojia, Deepika ; Shobith, Rangappa ; Nanjundaswamy, Shivananju ; Mason, Daniel J ; Bender, Andreas ; Basappa ; Rangappa, Kanchugarakoppal S ; Koeffler, H Phillip Lodola, Alessio

PloS one, 2014, Vol.9 (9), p.e107118-e107118 [Peer Reviewed Journal]

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3
Novel benzoxazine-based aglycones block glucose uptake in vivo by inhibiting glycosidases
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Novel benzoxazine-based aglycones block glucose uptake in vivo by inhibiting glycosidases

Bharathkumar, Hanumantharayappa ; Sundaram, Mahalingam S ; Jagadish, Swamy ; Paricharak, Shardul ; Hemshekhar, Mahadevappa ; Mason, Daniel ; Kemparaju, Kempaiah ; Girish, Kesturu S ; Basappa ; Bender, Andreas ; Rangappa, Kanchugarakoppal S Ganesan, A

PloS one, 2014, Vol.9 (7), p.e102759-e102759 [Peer Reviewed Journal]

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4
A One Pot Synthesis of Novel Bioactive Tri-Substitute-Condensed-Imidazopyridines that Targets Snake Venom Phospholipase A2
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A One Pot Synthesis of Novel Bioactive Tri-Substitute-Condensed-Imidazopyridines that Targets Snake Venom Phospholipase A2

Anilkumar, Nirvanappa C ; Sundaram, Mahalingam S ; Mohan, Chakrabhavi Dhananjaya ; Rangappa, Shobith ; Bulusu, Krishna C ; Fuchs, Julian E ; Girish, Kesturu S ; Bender, Andreas ; Basappa ; Rangappa, Kanchugarakoppal S Quintas, Luis Eduardo M

PloS one, 2015, Vol.10 (7), p.e0131896-e0131896 [Peer Reviewed Journal]

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5
MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy
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MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy

Becker, Lore ; Kling, Eva ; Schiller, Evelyn ; Zeh, Ramona ; Schrewe, Anja ; Hölter, Sabine M ; Mossbrugger, Ilona ; Calzada-Wack, Julia ; Strecker, Valentina ; Wittig, Ilka ; Dumitru, Iulia ; Wenz, Tina ; Bender, Andreas ; Aichler, Michaela ; Janik, Dirk ; Neff, Frauke ; Walch, Axel ; Quintanilla-Fend, Leticia ; Floss, Thomas ; Bekeredjian, Raffi ; Gailus-Durner, Valérie ; Fuchs, Helmut ; Wurst, Wolfgang ; Meitinger, Thomas ; Prokisch, Holger ; de Angelis, Martin Hrabě ; Klopstock, Thomas Lesnefsky, Edward J

PloS one, 2014, Vol.9 (12), p.e114918 [Peer Reviewed Journal]

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6
A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-orphanization
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A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-orphanization

van der Horst, Eelke ; Peironcely, Julio E ; Ijzerman, Adriaan P ; Beukers, Margot W ; Lane, Jonathan R ; van Vlijmen, Herman W T ; Emmerich, Michael T M ; Okuno, Yasushi ; Bender, Andreas

BMC bioinformatics, 2010-06-10, Vol.11 (1), p.316-316 [Peer Reviewed Journal]

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7
Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway
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Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway

Mohan, Chakrabhavi Dhananjaya ; Srinivasa, V ; Rangappa, Shobith ; Mervin, Lewis ; Mohan, Surender ; Paricharak, Shardul ; Baday, Sefer ; Li, Feng ; Shanmugam, Muthu K ; Chinnathambi, Arunachalam ; Zayed, M E ; Alharbi, Sulaiman Ali ; Bender, Andreas ; Sethi, Gautam ; Basappa ; Rangappa, Kanchugarakoppal S Quintas, Luis Eduardo M

PloS one, 2016, Vol.11 (4), p.e0153155

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8
Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity
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Identification of Novel Class of Triazolo-Thiadiazoles as Potent Inhibitors of Human Heparanase and their Anticancer Activity

Baburajeev, C. P ; Mohan, Chakrabhavi Dhananjaya ; Rangappa, Shobith ; Mason, Daniel J ; Fuchs, Julian E ; Bender, Andreas ; Barash, Uri ; Vlodavsky, Israel ; Basappa ; Rangappa, Kanchugarakoppal S

BMC cancer, 2017-03-31, Vol.17 (1), p.235-235 [Peer Reviewed Journal]

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9
Expression analysis of dopaminergic neurons in Parkinson’s disease and aging links transcriptional dysregulation of energy metabolism to cell death
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Expression analysis of dopaminergic neurons in Parkinson’s disease and aging links transcriptional dysregulation of energy metabolism to cell death

Elstner, Matthias ; Morris, Christopher M ; Heim, Katharina ; Bender, Andreas ; Mehta, Divya ; Jaros, Evelyn ; Klopstock, Thomas ; Meitinger, Thomas ; Turnbull, Douglass M ; Prokisch, Holger

Acta neuropathologica, 2011-07, Vol.122 (1), p.75-86 [Peer Reviewed Journal]

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10
Understanding and classifying metabolite space and metabolite-likeness
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Understanding and classifying metabolite space and metabolite-likeness

Peironcely, Julio E ; Reijmers, Theo ; Coulier, Leon ; Bender, Andreas ; Hankemeier, Thomas Willson, Richard C

PloS one, 2011, Vol.6 (12), p.e28966-e28966

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