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Results 1 - 10 of 25  for Great Falls College MSU

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1
Deorphaning the Macromolecular Targets of the Natural Anticancer Compound Doliculide
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Deorphaning the Macromolecular Targets of the Natural Anticancer Compound Doliculide

Schneider, Gisbert ; Reker, Daniel ; Chen, Tao ; Hauenstein, Kurt ; Schneider, Petra ; Altmann, KarlHeinz

Angewandte Chemie (International ed.), 2016-09-26, Vol.55 (40), p.12408-12411 [Peer Reviewed Journal]

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2
Multidimensional Design of Anticancer Peptides
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Multidimensional Design of Anticancer Peptides

Lin, Yen‐Chu ; Lim, Yi Fan ; Russo, Erica ; Schneider, Petra ; Bolliger, Lea ; Edenharter, Adriana ; Altmann, KarlHeinz ; Halin, Cornelia ; Hiss, Jan A ; Schneider, Gisbert

Angewandte Chemie (International ed.), 2015-08-24, Vol.54 (35), p.10370-10374 [Peer Reviewed Journal]

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3
Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate
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Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate

Gaugaz, Fabienne ; Chicca, Andrea ; Redondo-Horcajo, Mariano ; Barasoain, Isabel ; Díaz, J ; Altmann, Karl-Heinz

International journal of molecular sciences, 2019-03-05, Vol.20 (5), p.1113 [Peer Reviewed Journal]

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4
Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents
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Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents

Prota, Andrea E ; Bargsten, Katja ; Zurwerra, Didier ; Field, Jessica J ; Díaz, José Fernando ; Altmann, Karl-Heinz ; Steinmetz, Michel O

Science (American Association for the Advancement of Science), 2013-02-01, Vol.339 (6119), p.587-590 [Peer Reviewed Journal]

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5
Diversity through semisynthesis: the chemistry and biological activity of semisynthetic epothilone derivatives
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Diversity through semisynthesis: the chemistry and biological activity of semisynthetic epothilone derivatives

Altmann, Karl-Heinz ; Altmann, Karl-Heinz ; Gaugaz, Fabienne Z ; Gaugaz, Fabienne Z ; Schiess, Raphael ; Schiess, Raphael Appendino, Giovanni ; Appendino, Giovanni ; Banfi, Luca ; Banfi, Luca

Molecular diversity, 2011-05, Vol.15 (2), p.383-399 [Peer Reviewed Journal]

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6
High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cells
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High affinity and covalent-binding microtubule stabilizing agents show activity in chemotherapy-resistant acute myeloid leukemia cells

Pera, Benet ; Calvo-Vidal, M. Nieves ; Ambati, Srikanth ; Jordi, Michel ; Kahn, Alissa ; Díaz, J. Fernando ; Fang, Weishuo ; Altmann, Karl-Heinz ; Cerchietti, Leandro ; Moore, Malcolm A.S

Cancer Letters, 2015, Vol.368 (1), p.97-104 [Peer Reviewed Journal]

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7
Contextual Compound Screening for Improved Therapeutic Discovery
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Contextual Compound Screening for Improved Therapeutic Discovery

Evensen, Lasse ; Odlo, Kristin ; Micklem, David R ; Littlewood‐Evans, Amanda ; Wood, Jeanette ; Kuzniewski, Christian ; Altmann, KarlHeinz ; Hansen, Trond Vidar ; Lorens, James B

Chembiochem : a European journal of chemical biology, 2013-12-16, Vol.14 (18), p.2512-2518 [Peer Reviewed Journal]

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8
Total Synthesis and Biological Assessment of Mandelalide A
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Total Synthesis and Biological Assessment of Mandelalide A

Brütsch, Tobias Michael ; Bucher, Pascal ; Altmann, KarlHeinz

Chemistry : a European journal, 2016-01-22, Vol.22 (4), p.1292-1300

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9
A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin
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A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin

Menchon, Grégory ; Prota, Andrea E ; Lucena-Agell, Daniel ; Bucher, Pascal ; Jansen, Rolf ; Irschik, Herbert ; Müller, Rolf ; Paterson, Ian ; Díaz, J. Fernando ; Altmann, Karl-Heinz ; Steinmetz, Michel O

Nature communications, 2018-05-29, Vol.9 (1), p.2106-2106 [Peer Reviewed Journal]

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10
Total Synthesis of (−)‐Zampanolide and Structure–Activity Relationship Studies on (−)‐Dactylolide Derivatives
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Total Synthesis of (−)‐Zampanolide and Structure–Activity Relationship Studies on (−)‐Dactylolide Derivatives

Zurwerra, Didier ; Glaus, Florian ; Betschart, Leo ; Schuster, Julia ; Gertsch, Jürg ; Ganci, Walter ; Altmann, KarlHeinz

Chemistry : a European journal, 2012-12-21, Vol.18 (52), p.16868-16883

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