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1
Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate
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Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate

Gaugaz, Fabienne ; Chicca, Andrea ; Redondo-Horcajo, Mariano ; Barasoain, Isabel ; Díaz, J ; Altmann, Karl-Heinz

International journal of molecular sciences, 2019-03-05, Vol.20 (5), p.1113 [Peer Reviewed Journal]

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2
Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents
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Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents

Prota, Andrea E ; Bargsten, Katja ; Zurwerra, Didier ; Field, Jessica J ; Díaz, José Fernando ; Altmann, Karl-Heinz ; Steinmetz, Michel O

Science (American Association for the Advancement of Science), 2013-02-01, Vol.339 (6119), p.587-590 [Peer Reviewed Journal]

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3
Diversity through semisynthesis: the chemistry and biological activity of semisynthetic epothilone derivatives
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Diversity through semisynthesis: the chemistry and biological activity of semisynthetic epothilone derivatives

Altmann, Karl-Heinz ; Altmann, Karl-Heinz ; Gaugaz, Fabienne Z ; Gaugaz, Fabienne Z ; Schiess, Raphael ; Schiess, Raphael Appendino, Giovanni ; Appendino, Giovanni ; Banfi, Luca ; Banfi, Luca

Molecular diversity, 2011-05, Vol.15 (2), p.383-399 [Peer Reviewed Journal]

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4
The Binding Mode of Side Chain‐ and C3‐Modified Epothilones to Tubulin
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The Binding Mode of Side Chain‐ and C3‐Modified Epothilones to Tubulin

Erdélyi, Máté ; Navarro‐Vázquez, Armando ; Pfeiffer, Bernhard ; Kuzniewski, Christian N ; Felser, Andrea ; Widmer, Toni ; Gertsch, Jürg ; Pera, Benet ; Díaz, José Fernando ; Altmann, KarlHeinz ; Carlomagno, Teresa

ChemMedChem, 2010-06-07, Vol.5 (6), p.911-920 [Peer Reviewed Journal]

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5
Synthesis, Profiling, and Bioactive Conformation of trans ‐Cyclopropyl Epothilones
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Synthesis, Profiling, and Bioactive Conformation of trans ‐Cyclopropyl Epothilones

Kuzniewski, Christian N ; Glauser, Simon ; Gaugaz, Fabienne Z ; Schiess, Raphael ; Rodríguez‐Salarichs, Javier ; Vetterli, Stefan ; Horlacher, Oliver P ; Gertsch, Jürg ; Redondo‐Horcajo, Mariano ; Canales, Angeles ; Jiménez‐Barbero, Jesús ; Díaz, José Fernando ; Altmann, KarlHeinz

Helvetica chimica acta, 2019-04-26, Vol.102 (5), p.e1900078-n/a [Peer Reviewed Journal]

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6
Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones)
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Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones)

Jantsch, Andrea ; Nieto, Lidia ; Gertsch, Jürg ; Rodríguez-Salarichs, Javier ; Matesanz, Ruth ; Jiménez-Barbero, Jesús ; Díaz, J ; Canales, Ángeles ; Altmann, Karl-Heinz

Molecules (Basel, Switzerland), 2016-08-03, Vol.21 (8), p.1010 [Peer Reviewed Journal]

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7
The Impact of Cyclopropane Configuration on the Biological Activity of Cyclopropyl‐Epothilones
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The Impact of Cyclopropane Configuration on the Biological Activity of Cyclopropyl‐Epothilones

Gaugaz, Fabienne Z ; Redondo‐Horcajo, Mariano ; Barasoain, Isabel ; Díaz, J. Fernando ; Cobos‐Correa, Amanda ; Kaufmann, Markus ; Altmann, KarlHeinz

ChemMedChem, 2014-10, Vol.9 (10), p.2227-2232 [Peer Reviewed Journal]

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8
Design and Synthesis of 12‐Aza‐Epothilones (Azathilones)—“Non‐Natural” Natural Products with Potent Anticancer Activity
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Design and Synthesis of 12‐Aza‐Epothilones (Azathilones)—“Non‐Natural” Natural Products with Potent Anticancer Activity

Feyen, Fabian ; Gertsch, Jürg ; Wartmann, Markus ; Altmann, KarlHeinz

Angewandte Chemie (International ed.), 2006-09-04, Vol.45 (35), p.5880-5885 [Peer Reviewed Journal]

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9
The Chemistry and Biology of Epothilones—The Wheel Keeps Turning
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The Chemistry and Biology of Epothilones—The Wheel Keeps Turning

Altmann, KarlHeinz ; Pfeiffer, Bernhard ; Arseniyadis, Stellios ; Pratt, Benjamin A ; Nicolaou, K. C

ChemMedChem, 2007-04-16, Vol.2 (4), p.396-423 [Peer Reviewed Journal]

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10
Scaffolds for Microtubule Inhibition through Extensive Modification of the Epothilone Template
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Scaffolds for Microtubule Inhibition through Extensive Modification of the Epothilone Template

Cachoux, Frédéric ; Isarno, Thomas ; Wartmann, Markus ; Altmann, KarlHeinz

Angewandte Chemie (International ed.), 2005-11-18, Vol.44 (45), p.7469-7473 [Peer Reviewed Journal]

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