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Serendipitous Discovery of a Potent Influenza Virus A Neuraminidase Inhibitor

Mohan, Sankar ; Kerry, Philip S. ; Bance, Nicole ; Niikura, Masahiro ; Pinto, B. Mario

Angewandte Chemie, 20 January 2014, Vol.126(4), pp.1094-1098 [Peer Reviewed Journal]

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Stabilizer‐Guided Inhibition of Protein–Protein Interactions

Milroy, Lech‐Gustav ; Bartel, Maria ; Henen, Morkos A. ; Leysen, Seppe ; Adriaans, Joris M. C. ; Brunsveld, Luc ; Landrieu, Isabelle ; Ottmann, Christian

Angewandte Chemie, 21 December 2015, Vol.127(52), pp.15946-15950 [Peer Reviewed Journal]

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Synthesis of a Natural Product‐Like Compound Collection through Oxidative Cleavage and Cyclization of Linear Peptides

Petersen, Rico ; Le Quement, Sebastian T. ; Nielsen, Thomas E.

Angewandte Chemie, 27 October 2014, Vol.126(44), pp.11972-11976 [Peer Reviewed Journal]

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Structure‐Based Approach To Improve a Small‐Molecule Inhibitor by the Use of a Competitive Peptide Ligand

Ono, Katsuki ; Takeuchi, Koh ; Ueda, Hiroshi ; Morita, Yasuhiro ; Tanimura, Ryuji ; Shimada, Ichio ; Takahashi, Hideo

Angewandte Chemie, 03 March 2014, Vol.126(10), pp.2635-2639 [Peer Reviewed Journal]

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Crowdsourcing Natural Products Discovery to Access Uncharted Dimensions of Fungal Metabolite Diversity

Du, Lin ; Robles, Andrew J. ; King, Jarrod B. ; Powell, Douglas R. ; Miller, Andrew N. ; Mooberry, Susan L. ; Cichewicz, Robert H.

Angewandte Chemie, 13 January 2014, Vol.126(3), pp.823-828 [Peer Reviewed Journal]

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Allosteric Tuning of Caspase‐7: A Fragment‐Based Drug Discovery Approach

Vance, Nicholas R. ; Gakhar, Lokesh ; Spies, M. Ashley

Angewandte Chemie, 13 November 2017, Vol.129(46), pp.14635-14639 [Peer Reviewed Journal]

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Multitarget Drug Discovery for Alzheimer's Disease: Triazinones as BACE‐1 and GSK‐3β Inhibitors

Prati, Federica ; De Simone, Angela ; Bisignano, Paola ; Armirotti, Andrea ; Summa, Maria ; Pizzirani, Daniela ; Scarpelli, Rita ; Perez, Daniel I. ; Andrisano, Vincenza ; Perez‐Castillo, Ana ; Monti, Barbara ; Massenzio, Francesca ; Polito, Letizia ; Racchi, Marco ; Favia, Angelo D. ; Bottegoni, Giovanni ; Martinez, Ana ; Bolognesi, Maria Laura ; Cavalli, Andrea

Angewandte Chemie, 26 January 2015, Vol.127(5), pp.1598-1602 [Peer Reviewed Journal]

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Optimization of TRPV6 Calcium Channel Inhibitors Using a 3D Ligand‐Based Virtual Screening Method

Simonin, Céline ; Awale, Mahendra ; Brand, Michael ; Van Deursen, Ruud ; Schwartz, Julian ; Fine, Michael ; Kovacs, Gergely ; Häfliger, Pascal ; Gyimesi, Gergely ; Sithampari, Abilashan ; Charles, Roch‐Philippe ; Hediger, Matthias A. ; Reymond, Jean‐Louis

Angewandte Chemie, 01 December 2015, Vol.127(49), pp.14961-14965 [Peer Reviewed Journal]

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Application of Fragment‐Based Screening to the Design of Inhibitors of Escherichia coli DsbA

Adams, Luke A. ; Sharma, Pooja ; Mohanty, Biswaranjan ; Ilyichova, Olga V. ; Mulcair, Mark D. ; Williams, Martin L. ; Gleeson, Ellen C. ; Totsika, Makrina ; Doak, Bradley C. ; Caria, Sofia ; Rimmer, Kieran ; Horne, James ; Shouldice, Stephen R. ; Vazirani, Mansha ; Headey, Stephen J. ; Plumb, Brent R. ; Martin, Jennifer L. ; Heras, Begoña ; Simpson, Jamie S. ; Scanlon, Martin J.

Angewandte Chemie, 09 February 2015, Vol.127(7), pp.2207-2212 [Peer Reviewed Journal]

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Discovery of Inhibitors of Shiga Toxin Type 2 by On‐Plate Generation and Screening of a Focused Compound Library

Dasgupta, Somnath ; Kitov, Pavel I. ; Sadowska, Joanna M. ; Bundle, David R.

Angewandte Chemie, 03 February 2014, Vol.126(6), pp.1536-1541 [Peer Reviewed Journal]

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