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Results 1 - 10 of 22  for Great Falls College MSU

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1
Synthesis and Biological Activity of 7,8,9‐Trideoxy‐ and 7R DesTHP‐Peloruside A
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Synthesis and Biological Activity of 7,8,9‐Trideoxy‐ and 7R DesTHP‐Peloruside A

Wullschleger, Christoph W ; Gertsch, Jürg ; Altmann, KarlHeinz

Chemistry : a European journal, 2013-09-23, Vol.19 (39), p.13105-13111

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2
Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate
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Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate

Gaugaz, Fabienne ; Chicca, Andrea ; Redondo-Horcajo, Mariano ; Barasoain, Isabel ; Díaz, J ; Altmann, Karl-Heinz

International journal of molecular sciences, 2019-03-05, Vol.20 (5), p.1113 [Peer Reviewed Journal]

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3
Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands
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Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands

Balaguer, Francisco de Asís ; Mühlethaler, Tobias ; Estévez-Gallego, Juan ; Calvo, Enrique ; Giménez-Abián, Juan Francisco ; Risinger, April L ; Sorensen, Erik J ; Vanderwal, Christopher D ; Altmann, Karl-Heinz ; Mooberry, Susan L ; Steinmetz, Michel O ; Oliva, María Ángela ; Prota, Andrea E ; Díaz, J Fernando

International journal of molecular sciences, 2019-03-20, Vol.20 (6), p.1392 [Peer Reviewed Journal]

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4
The Binding Mode of Side Chain‐ and C3‐Modified Epothilones to Tubulin
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The Binding Mode of Side Chain‐ and C3‐Modified Epothilones to Tubulin

Erdélyi, Máté ; Navarro‐Vázquez, Armando ; Pfeiffer, Bernhard ; Kuzniewski, Christian N ; Felser, Andrea ; Widmer, Toni ; Gertsch, Jürg ; Pera, Benet ; Díaz, José Fernando ; Altmann, KarlHeinz ; Carlomagno, Teresa

ChemMedChem, 2010-06-07, Vol.5 (6), p.911-920 [Peer Reviewed Journal]

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5
A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin
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A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin

Menchon, Grégory ; Prota, Andrea E ; Lucena-Agell, Daniel ; Bucher, Pascal ; Jansen, Rolf ; Irschik, Herbert ; Müller, Rolf ; Paterson, Ian ; Díaz, J. Fernando ; Altmann, Karl-Heinz ; Steinmetz, Michel O

Nature communications, 2018-05-29, Vol.9 (1), p.2106-2106 [Peer Reviewed Journal]

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6
Total Synthesis of (−)‐Zampanolide and Structure–Activity Relationship Studies on (−)‐Dactylolide Derivatives
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Total Synthesis of (−)‐Zampanolide and Structure–Activity Relationship Studies on (−)‐Dactylolide Derivatives

Zurwerra, Didier ; Glaus, Florian ; Betschart, Leo ; Schuster, Julia ; Gertsch, Jürg ; Ganci, Walter ; Altmann, KarlHeinz

Chemistry : a European journal, 2012-12-21, Vol.18 (52), p.16868-16883

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7
Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell Migration
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Zampanolide, a Microtubule-Stabilizing Agent, Is Active in Resistant Cancer Cells and Inhibits Cell Migration

Field, Jessica J ; Northcote, Peter T ; Paterson, Ian ; Altmann, Karl-Heinz ; Díaz, J Fernando ; Miller, John H

International journal of molecular sciences, 2017-05-03, Vol.18 (5), p.971 [Peer Reviewed Journal]

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8
Synthesis, Profiling, and Bioactive Conformation of trans ‐Cyclopropyl Epothilones
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Synthesis, Profiling, and Bioactive Conformation of trans ‐Cyclopropyl Epothilones

Kuzniewski, Christian N ; Glauser, Simon ; Gaugaz, Fabienne Z ; Schiess, Raphael ; Rodríguez‐Salarichs, Javier ; Vetterli, Stefan ; Horlacher, Oliver P ; Gertsch, Jürg ; Redondo‐Horcajo, Mariano ; Canales, Angeles ; Jiménez‐Barbero, Jesús ; Díaz, José Fernando ; Altmann, KarlHeinz

Helvetica chimica acta, 2019-04-26, Vol.102 (5), p.e1900078-n/a [Peer Reviewed Journal]

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9
Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones)
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Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones)

Jantsch, Andrea ; Nieto, Lidia ; Gertsch, Jürg ; Rodríguez-Salarichs, Javier ; Matesanz, Ruth ; Jiménez-Barbero, Jesús ; Díaz, J ; Canales, Ángeles ; Altmann, Karl-Heinz

Molecules (Basel, Switzerland), 2016-08-03, Vol.21 (8), p.1010 [Peer Reviewed Journal]

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10
The High‐Resolution Solution Structure of Epothilone A Bound to Tubulin: An Understanding of the Structure–Activity Relationships for a Powerful Class of Antitumor Agents
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The High‐Resolution Solution Structure of Epothilone A Bound to Tubulin: An Understanding of the Structure–Activity Relationships for a Powerful Class of Antitumor Agents

Carlomagno, Teresa ; Blommers, Marcel J. J ; Meiler, Jens ; Jahnke, Wolfgang ; Schupp, Thomas ; Petersen, Frank ; Schinzer, Dieter ; Altmann, KarlHeinz ; Griesinger, Christian

Angewandte Chemie (International ed.), 2003-06-06, Vol.42 (22), p.2511-2515 [Peer Reviewed Journal]

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