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Results 1 - 10 of 1,403  for Great Falls College MSU

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1
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
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ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

Souers, Andrew J ; Leverson, Joel D ; Boghaert, Erwin R ; Ackler, Scott L ; Catron, Nathaniel D ; Chen, Jun ; Dayton, Brian D ; Ding, Hong ; Enschede, Sari H ; Fairbrother, Wayne J ; Huang, David C S ; Hymowitz, Sarah G ; Jin, Sha ; Khaw, Seong Lin ; Kovar, Peter J ; Lam, Lloyd T ; Lee, Jackie ; Maecker, Heather L ; Marsh, Kennan C ; Mason, Kylie D ; Mitten, Michael J ; Nimmer, Paul M ; Oleksijew, Anatol ; Park, Chang H ; Park, Cheol-Min ; Phillips, Darren C ; Roberts, Andrew W ; Sampath, Deepak ; Seymour, John F ; Smith, Morey L ; Sullivan, Gerard M ; Tahir, Stephen K ; Tse, Chris ; Wendt, Michael D ; Xiao, Yu ; Xue, John C ; Zhang, Haichao ; Humerickhouse, Rod A ; Rosenberg, Saul H ; Elmore, Steven W

Nature medicine, 2013-02, Vol.19 (2), p.202-208 [Peer Reviewed Journal]

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2
Secretory mechanisms and intercellular transfer of microRNAs in living cells
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Secretory mechanisms and intercellular transfer of microRNAs in living cells

Kosaka, Nobuyoshi ; Iguchi, Haruhisa ; Yoshioka, Yusuke ; Takeshita, Fumitaka ; Matsuki, Yasushi ; Ochiya, Takahiro

The Journal of biological chemistry, 2010-06-04, Vol.285 (23), p.17442-17452 [Peer Reviewed Journal]

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3
Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models
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Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models

Eberlein, Catherine A ; Stetson, Daniel ; Markovets, Aleksandra A ; Al-Kadhimi, Katherine J ; Lai, Zhongwu ; Fisher, Paul R ; Meador, Catherine B ; Spitzler, Paula ; Ichihara, Eiki ; Ross, Sarah J ; Ahdesmaki, Miika J ; Ahmed, Ambar ; Ratcliffe, Laura E ; O'Brien, Elizabeth L Christey ; Barnes, Claire H ; Brown, Henry ; Smith, Paul D ; Dry, Jonathan R ; Beran, Garry ; Thress, Kenneth S ; Dougherty, Brian ; Pao, William ; Cross, Darren A E

Cancer research (Chicago, Ill.), 2015-06-15, Vol.75 (12), p.2489-2500 [Peer Reviewed Journal]

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4
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
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Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

Chang, Jianhui ; Wang, Yingying ; Shao, Lijian ; Laberge, Remi-Martin ; Demaria, Marco ; Campisi, Judith ; Janakiraman, Krishnamurthy ; Sharpless, Norman E ; Ding, Sheng ; Feng, Wei ; Luo, Yi ; Wang, Xiaoyan ; Aykin-Burns, Nukhet ; Krager, Kimberly ; Ponnappan, Usha ; Hauer-Jensen, Martin ; Meng, Aimin ; Zhou, Daohong

Nature medicine, 2016-01, Vol.22 (1), p.78-83 [Peer Reviewed Journal]

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5
Preclinical studies of gilteritinib, a next-generation FLT3 inhibitor
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Preclinical studies of gilteritinib, a next-generation FLT3 inhibitor

Lee, Lauren Y ; Hernandez, Daniela ; Rajkhowa, Trivikram ; Smith, Samuel C ; Raman, Jayant Ranganathan ; Nguyen, Bao ; Small, Donald ; Levis, Mark

Blood, 2017-01-12, Vol.129 (2), p.257-260 [Peer Reviewed Journal]

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6
Diketopyrrolopyrrole–Triphenylamine Organic Nanoparticles as Multifunctional Reagents for Photoacoustic Imaging-Guided Photodynamic/Photothermal Synergistic Tumor Therapy
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Diketopyrrolopyrrole–Triphenylamine Organic Nanoparticles as Multifunctional Reagents for Photoacoustic Imaging-Guided Photodynamic/Photothermal Synergistic Tumor Therapy

Cai, Yu ; Liang, Pingping ; Tang, Qianyun ; Yang, Xiaoyan ; Si, Weili ; Huang, Wei ; Zhang, Qi ; Dong, Xiaochen

ACS nano, 2017-01-24, Vol.11 (1), p.1054-1063 [Peer Reviewed Journal]

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7
Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)
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Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)

Leverson, J D ; Zhang, H ; Chen, J ; Tahir, S K ; Phillips, D C ; Xue, J ; Nimmer, P ; Jin, S ; Smith, M ; Xiao, Y ; Kovar, P ; Tanaka, A ; Bruncko, M ; Sheppard, G S ; Wang, L ; Gierke, S ; Kategaya, L ; Anderson, D J ; Wong, C ; Eastham-Anderson, J ; Ludlam, M J C ; Sampath, D ; Fairbrother, W J ; Wertz, I ; Rosenberg, S H ; Tse, C ; Elmore, S W ; Souers, A J

Cell death & disease, 2015-01-15, Vol.6 (1), p.e1590-e1590 [Peer Reviewed Journal]

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8
Discovery of a Potent and Selective EGFR Inhibitor (AZD9291) of Both Sensitizing and T790M Resistance Mutations That Spares the Wild Type Form of the Receptor
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Discovery of a Potent and Selective EGFR Inhibitor (AZD9291) of Both Sensitizing and T790M Resistance Mutations That Spares the Wild Type Form of the Receptor

Finlay, M. Raymond V ; Anderton, Mark ; Ashton, Susan ; Ballard, Peter ; Bethel, Paul A ; Box, Matthew R ; Bradbury, Robert H ; Brown, Simon J ; Butterworth, Sam ; Campbell, Andrew ; Chorley, Christopher ; Colclough, Nicola ; Cross, Darren A. E ; Currie, Gordon S ; Grist, Matthew ; Hassall, Lorraine ; Hill, George B ; James, Daniel ; James, Michael ; Kemmitt, Paul ; Klinowska, Teresa ; Lamont, Gillian ; Lamont, Scott G ; Martin, Nathaniel ; McFarland, Heather L ; Mellor, Martine J ; Orme, Jonathon P ; Perkins, David ; Perkins, Paula ; Richmond, Graham ; Smith, Peter ; Ward, Richard A ; Waring, Michael J ; Whittaker, David ; Wells, Stuart ; Wrigley, Gail L

Journal of medicinal chemistry, 2014-10-23, Vol.57 (20), p.8249-8267 [Peer Reviewed Journal]

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9
Exosome secretion is a key pathway for clearance of pathological TDP-43
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Exosome secretion is a key pathway for clearance of pathological TDP-43

Iguchi, Yohei ; Eid, Lara ; Parent, Martin ; Soucy, Geneviève ; Bareil, Christine ; Riku, Yuichi ; Kawai, Kaori ; Takagi, Shinnosuke ; Yoshida, Mari ; Katsuno, Masahisa ; Sobue, Gen ; Julien, Jean-Pierre

Brain (London, England : 1878), 2016-12, Vol.139 (Pt 12), p.3187-3201 [Peer Reviewed Journal]

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10
Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors
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Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors

Zhu, Yi ; Tchkonia, Tamara ; Fuhrmann‐Stroissnigg, Heike ; Dai, Haiming M ; Ling, Yuanyuan Y ; Stout, Michael B ; Pirtskhalava, Tamar ; Giorgadze, Nino ; Johnson, Kurt O ; Giles, Cory B ; Wren, Jonathan D ; Niedernhofer, Laura J ; Robbins, Paul D ; Kirkland, James L

Aging cell, 2016-06, Vol.15 (3), p.428-435 [Peer Reviewed Journal]

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