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Results 1 - 10 of 196  for Great Falls College MSU

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Potent taccalonolides, AF and AJ, inform significant structure-activity relationships and tubulin as the binding site of these microtubule stabilizers

Li, Jing ; Risinger, April L ; Peng, Jiangnan ; Chen, Zhongliang ; Hu, Lihong ; Mooberry, Susan L

Journal of the American Chemical Society, 30 November 2011, Vol.133(47), pp.19064-7 [Peer Reviewed Journal]

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Abstract 5481: Differential inhibition of microtubule-dependent transport and signaling pathways important for cancer cell growth and survival
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Abstract 5481: Differential inhibition of microtubule-dependent transport and signaling pathways important for cancer cell growth and survival

Rohena, Cristina C. ; Mooberry, Susan L.

Cancer Research, 10/01/2014, Vol.74(19 Supplement), pp.5481-5481 [Peer Reviewed Journal]

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Synthetic reactions with rare taccalonolides reveal the value of C-22,23 epoxidation for microtubule stabilizing potency

Peng, Jiangnan ; Risinger, April L ; Li, Jing ; Mooberry, Susan L

Journal of medicinal chemistry, 24 July 2014, Vol.57(14), pp.6141-9 [Peer Reviewed Journal]

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How to deal with low-resolution target structures: using SAR, ensemble docking, hydropathic analysis, and 3D-QSAR to definitively map the αβ-tubulin colchicine site.

Da, Chenxiao ; Mooberry, Susan L ; Gupton, John T ; Kellogg, Glen E Da, Chenxiao (correspondence author) ; Da, Chenxiao (record owner)

Journal of medicinal chemistry, September 26, 2013, Vol.56(18), pp.7382-7395 [Peer Reviewed Journal]

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Synthesis and biological activities of (R)- and (S)-N-(4-Methoxyphenyl)-N,2,6-trimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-aminium chloride as potent cytotoxic antitubulin agents.

Gangjee, Aleem ; Zhao, Ying ; Hamel, Ernest ; Westbrook, Cara ; Mooberry, Susan L Gangjee, Aleem (correspondence author) ; Gangjee, Aleem (record owner)

Journal of medicinal chemistry, September 8, 2011, Vol.54(17), pp.6151-6155 [Peer Reviewed Journal]

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Abstract 4910: Eribulin rapidly impairs TGF-β signaling
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Abstract 4910: Eribulin rapidly impairs TGF-β signaling

Kaul, Roma ; Risinger, April L. ; Mooberry, Susan L.

Cancer Research, 07/01/2017, Vol.77(13 Supplement), pp.4910-4910 [Peer Reviewed Journal]

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Abstract 2030: Eribulin disrupts TGF-β-mediated Smad2/3-dependent transcription of EMT promoting proteins in triple negative breast cancer cells
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Abstract 2030: Eribulin disrupts TGF-β-mediated Smad2/3-dependent transcription of EMT promoting proteins in triple negative breast cancer cells

Kaul, Roma ; Risinger, April L. ; Mooberry, Susan L.

Cancer Research, 07/01/2018, Vol.78(13 Supplement), pp.2030-2030 [Peer Reviewed Journal]

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Abstract 836: Potent antitubulin and antitumor activities influenced by the 3-D conformational shape of bicyclic fused pyrimidines
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Abstract 836: Potent antitubulin and antitumor activities influenced by the 3-D conformational shape of bicyclic fused pyrimidines

Gangjee, Aleem ; Xiang, Weiguo ; Mooberry, Susan L. ; Hamel, Ernest

Cancer Research, 10/01/2014, Vol.74(19 Supplement), pp.836-836 [Peer Reviewed Journal]

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Abstract 349: Eribulin induces cortical localization of E-cadherin, p120-catenin and beta-catenin in breast cancer cells
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Abstract 349: Eribulin induces cortical localization of E-cadherin, p120-catenin and beta-catenin in breast cancer cells

Clark, Alison D. ; Dybdal-Hargreaves, Nicholas F. ; Mooberry, Susan L.

Cancer Research, 07/01/2017, Vol.77(13 Supplement), pp.349-349 [Peer Reviewed Journal]

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Abstract 5545: Deguelin selectively inhibits proliferation of luminal androgen receptor (LAR) triple-negative breast cancer cells
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Abstract 5545: Deguelin selectively inhibits proliferation of luminal androgen receptor (LAR) triple-negative breast cancer cells

Robles, Andrew J. ; Cai, Shengxin ; Cichewicz, Robert H. ; Mooberry, Susan L.

Cancer Research, 08/01/2015, Vol.75(15 Supplement), pp.5545-5545 [Peer Reviewed Journal]

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