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1
Identifying hotspots in land use land cover change and the drivers in a semi-arid region of India
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Identifying hotspots in land use land cover change and the drivers in a semi-arid region of India

Duraisamy, Vijayasekaran ; Bendapudi, Ramkumar ; Jadhav, Ajit

Environmental monitoring and assessment, 2018, Vol.190 (9), p.1-21 [Peer Reviewed Journal]

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2
Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo
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Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo

Najm, Fadi J ; Madhavan, Mayur ; Zaremba, Anita ; Shick, Elizabeth ; Karl, Robert T ; Factor, Daniel C ; Miller, Tyler E ; Nevin, Zachary S ; Kantor, Christopher ; Sargent, Alex ; Quick, Kevin L ; Schlatzer, Daniela M ; Tang, Hong ; Papoian, Ruben ; Brimacombe, Kyle R ; Shen, Min ; Boxer, Matthew B ; Jadhav, Ajit ; Robinson, Andrew P ; Podojil, Joseph R ; Miller, Stephen D ; Miller, Robert H ; Tesar, Paul J

Nature (London), 2015, Vol.522 (7555), p.216-220 [Peer Reviewed Journal]

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3
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells
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High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells

Lesley A. Mathews Griner ; Rajarshi Guha ; Paul Shinn ; Ryan M. Young ; Jonathan M. Keller ; Dongbo Liu ; Ian S. Goldlust ; Adam Yasgar ; Crystal McKnight ; Matthew B. Boxer ; Damien Y. Duveau ; Jian-Kang Jiang ; Sam Michael ; Tim Mierzwa ; Wenwei Huang ; Martin J. Walsh ; Bryan T. Mott ; Paresma Patel ; William Leister ; David J. Maloney ; Christopher A. Leclair ; Ganesha Rai ; Ajit Jadhav ; Brian D. Peyser ; Christopher P. Austin ; Scott E. Martin ; Anton Simeonov ; Marc Ferrer ; Louis M. Staudt ; Craig J. Thomas

Proceedings of the National Academy of Sciences - PNAS, 2014, Vol.111 (6), p.2349-2354 [Peer Reviewed Journal]

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4
Quantitative high-throughput screening: A titration-based approach that efficiently identifies biological activities in large chemical libraries
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Quantitative high-throughput screening: A titration-based approach that efficiently identifies biological activities in large chemical libraries

James Inglese ; Douglas S. Auld ; Ajit Jadhav ; Ronald L. Johnson ; Anton Simeonov ; Adam Yasgar ; Wei Zheng ; Christopher P. Austin

Proceedings of the National Academy of Sciences - PNAS, 2006, Vol.103 (31), p.11473-11478 [Peer Reviewed Journal]

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5
A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses
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A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses

Liang, Qin ; Dexheimer, Thomas S ; Zhang, Ping ; Rosenthal, Andrew S ; Villamil, Mark A ; You, Changjun ; Zhang, Qiuting ; Chen, Junjun ; Ott, Christine A ; Sun, Hongmao ; Luci, Diane K ; Yuan, Bifeng ; Simeonov, Anton ; Jadhav, Ajit ; Xiao, Hui ; Wang, Yinsheng ; Maloney, David J ; Zhuang, Zhihao

Nature chemical biology, 2014, Vol.10 (4), p.298-304 [Peer Reviewed Journal]

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6
Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition
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Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition

Gormally, Michael V ; Dexheimer, Thomas S ; Marsico, Giovanni ; Sanders, Deborah A ; Lowe, Christopher ; Matak-Vinković, Dijana ; Michael, Sam ; Jadhav, Ajit ; Rai, Ganesha ; Maloney, David J ; Simeonov, Anton ; Balasubramanian, Shankar

Nature communications, 2014, Vol.5 (1), p.5165 [Peer Reviewed Journal]

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7
Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy
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Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy

Kenny, Hilary A ; Lal-Nag, Madhu ; White, Erin A ; Shen, Min ; Chiang, Chun-Yi ; Mitra, Anirban K ; Zhang, Yilin ; Curtis, Marion ; Schryver, Elizabeth M ; Bettis, Sam ; Jadhav, Ajit ; Boxer, Matthew B ; Li, Zhuyin ; Ferrer, Marc ; Lengyel, Ernst

Nature communications, 2015, Vol.6 (1), p.6220 [Peer Reviewed Journal]

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8
Unexplored therapeutic opportunities in the human genome
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Unexplored therapeutic opportunities in the human genome

Oprea, Tudor I ; Bologa, Cristian G ; Brunak, Søren ; Campbell, Allen ; Gan, Gregory N ; Gaulton, Anna ; Gomez, Shawn M ; Guha, Rajarshi ; Hersey, Anne ; Holmes, Jayme ; Jadhav, Ajit ; Jensen, Lars Juhl ; Johnson, Gary L ; Karlson, Anneli ; Leach, Andrew R ; Ma'ayan, Avi ; Malovannaya, Anna ; Mani, Subramani ; Mathias, Stephen L ; McManus, Michael T ; Meehan, Terrence F ; von Mering, Christian ; Muthas, Daniel ; Nguyen, Dac-Trung ; Overington, John P ; Papadatos, George ; Qin, Jun ; Reich, Christian ; Roth, Bryan L ; Schürer, Stephan C ; Simeonov, Anton ; Sklar, Larry A ; Southall, Noel ; Tomita, Susumu ; Tudose, Ilinca ; Ursu, Oleg ; Vidović, Dušica ; Waller, Anna ; Westergaard, David ; Yang, Jeremy J ; Zahoránszky-Köhalmi, Gergely

Nature reviews. Drug discovery, 2018, Vol.17 (5), p.317-332 [Peer Reviewed Journal]

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9
Compound Cytotoxicity Profiling Using Quantitative High-Throughput Screening
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Compound Cytotoxicity Profiling Using Quantitative High-Throughput Screening

Xia, Menghang ; Huang, Ruili ; Witt, Kristine L ; Southall, Noel ; Fostel, Jennifer ; Cho, Ming-Hsuang ; Jadhav, Ajit ; Smith, Cynthia S ; Inglese, James ; Portier, Christopher J ; Tice, Raymond R ; Austin, Christopher P

Environmental health perspectives, 2008, Vol.116 (3), p.284-291 [Peer Reviewed Journal]

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10
Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors
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Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors

King, Oliver N F ; Li, Xuan Shirley ; Sakurai, Masaaki ; Kawamura, Akane ; Rose, Nathan R ; Ng, Stanley S ; Quinn, Amy M ; Rai, Ganesha ; Mott, Bryan T ; Beswick, Paul ; Klose, Robert J ; Oppermann, Udo ; Jadhav, Ajit ; Heightman, Tom D ; Maloney, David J ; Schofield, Christopher J ; Simeonov, Anton Cotterill, Sue

PloS one, 2010-11-23, Vol.5 (11), p.e15535 [Peer Reviewed Journal]

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