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An extra-uterine system to physiologically support the extreme premature lamb
An extra-uterine system to physiologically support the extreme premature lamb
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An extra-uterine system to physiologically support the extreme premature lamb

Partridge, Emily A ; Davey, Marcus G ; Hornick, Matthew A ; McGovern, Patrick E ; Mejaddam, Ali Y ; Vrecenak, Jesse D ; Mesas-Burgos, Carmen ; Olive, Aliza ; Caskey, Robert C ; Weiland, Theodore R ; Han, Jiancheng ; Schupper, Alexander J ; Connelly, James T ; Dysart, Kevin C ; Rychik, Jack ; Hedrick, Holly L ; Peranteau, William H ; Flake, Alan W

Nature communications, 2017-04-25, Vol.8 (1), p.15112-15112 [Peer Reviewed Journal]

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Quantitative contrast-enhanced ultrasound of the brain on twin fetal lambs maintained by the extrauterine environment for neonatal development (EXTEND): initial experience
Quantitative contrast-enhanced ultrasound of the brain on twin fetal lambs maintained by the extrauterine environment for neonatal development (EXTEND): initial experience
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Quantitative contrast-enhanced ultrasound of the brain on twin fetal lambs maintained by the extrauterine environment for neonatal development (EXTEND): initial experience

Sridharan, Anush ; Lawrence, Kendall M ; Martin-Saavedra, Juan S ; Davey, Marcus G ; Flake, Alan W ; Didier, Ryne A

Pediatric radiology, 2020-09-01, Vol.51 (1), p.103-111 [Peer Reviewed Journal]

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3
Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep
Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep
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Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep

MacKenzie, Tippi C ; Shaaban, Aimen F ; Moseley, AnneMarie B ; Flake, Alan W ; Deans, Robert ; Liechty, Kenneth W ; Marshak, Daniel R ; Radu, Antoneta

Nature medicine, 2000-11, Vol.6 (11), p.1282-1286 [Peer Reviewed Journal]

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4
Safety and efficacy of fetal surgery techniques to close a spina bifida defect in the fetal lamb model: A systematic review
Safety and efficacy of fetal surgery techniques to close a spina bifida defect in the fetal lamb model: A systematic review
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Safety and efficacy of fetal surgery techniques to close a spina bifida defect in the fetal lamb model: A systematic review

Joyeux, Luc ; De Bie, Felix ; Danzer, Enrico ; Van Mieghem, Tim ; Flake, Alan W ; Deprest, Jan

Prenatal diagnosis, 2018-03, Vol.38 (4), p.231-242 [Peer Reviewed Journal]

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5
Improved pulmonary function in the nitrofen model of congenital diaphragmatic hernia following prenatal maternal dexamethasone and/or sildenafil
Improved pulmonary function in the nitrofen model of congenital diaphragmatic hernia following prenatal maternal dexamethasone and/or sildenafil
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Improved pulmonary function in the nitrofen model of congenital diaphragmatic hernia following prenatal maternal dexamethasone and/or sildenafil

Burgos, Carmen Mesas ; Pearson, Erik G ; Davey, Marcus ; Riley, John ; Jia, Huimin ; Laje, Pablo ; Flake, Alan W ; Peranteau, William H

Pediatric research, 2016-10, Vol.80 (4), p.577-585 [Peer Reviewed Journal]

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6
Premiere use of Integra™ artificial skin to close an extensive fetal skin defect during open in utero repair of myelomeningocele
Premiere use of Integra™ artificial skin to close an extensive fetal skin defect during open in utero repair of myelomeningocele
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Premiere use of Integra™ artificial skin to close an extensive fetal skin defect during open in utero repair of myelomeningocele

Meuli, Martin ; Meuli-Simmen, Claudia ; Flake, Alan W ; Zimmermann, Roland ; Ochsenbein, Nicole ; Scheer, Ianina ; Mazzone, Luca ; Moehrlen, Ueli

Pediatric surgery international, 2013-12, Vol.29 (12), p.1321-1326 [Peer Reviewed Journal]

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7
Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector
Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector
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Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector

Larson, Peter J ; Johnson, Fred ; Couto, Linda B ; Chew, Amy J ; Flake, Alan W ; Manno, Catherine S ; Skarsgard, Erik ; McClelland, Alan ; Scallan, Ciaran ; High, Katherine A ; Ragni, Margaret V ; J Tai, Shing ; Arruda, Valder ; Herzog, Roland W ; Kay, Mark A ; Glader, Bertil

Nature genetics, 2000-03, Vol.24 (3), p.257-261 [Peer Reviewed Journal]

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8
Maternal alloantibodies induce a postnatal immune response that limits engraftment following in utero hematopoietic cell transplantation in mice
Maternal alloantibodies induce a postnatal immune response that limits engraftment following in utero hematopoietic cell transplantation in mice
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Maternal alloantibodies induce a postnatal immune response that limits engraftment following in utero hematopoietic cell transplantation in mice

Merianos, Demetri J ; Tiblad, Eleonor ; Santore, Matthew T ; Todorow, Carlyn A ; Laje, Pablo ; Endo, Masayuki ; Zoltick, Philip W ; Flake, Alan W

The Journal of clinical investigation, 2009-09, Vol.119 (9), p.2590-2600 [Peer Reviewed Journal]

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9
Technical feasibility of umbilical cannulation in midgestation lambs supported by the EXTra‐uterine Environment for Neonatal Development (EXTEND)
Technical feasibility of umbilical cannulation in midgestation lambs supported by the EXTra‐uterine Environment for Neonatal Development (EXTEND)
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Technical feasibility of umbilical cannulation in midgestation lambs supported by the EXTra‐uterine Environment for Neonatal Development (EXTEND)

Hornick, Matthew A ; Mejaddam, Ali Y ; McGovern, Patrick E ; Hwang, Grace ; Han, Jiancheng ; Peranteau, William H ; Partridge, Emily A ; Davey, Marcus G ; Flake, Alan W

Artificial organs, 2019-12, Vol.43 (12), p.1154-1161 [Peer Reviewed Journal]

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10
Umbilical cannulation optimizes circuit flows in premature lambs supported by the EXTra‐uterine Environment for Neonatal Development (EXTEND)
Umbilical cannulation optimizes circuit flows in premature lambs supported by the EXTra‐uterine Environment for Neonatal Development (EXTEND)
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Umbilical cannulation optimizes circuit flows in premature lambs supported by the EXTra‐uterine Environment for Neonatal Development (EXTEND)

Hornick, Matthew A ; Davey, Marcus G ; Partridge, Emily A ; Mejaddam, Ali Y ; McGovern, Patrick E ; Olive, Aliza M ; Hwang, Grace ; Kim, Jenny ; Castillo, Orlando ; Young, Kathleen ; Han, Jiancheng ; Zhao, Sheng ; Connelly, James T ; Dysart, Kevin C ; Rychik, Jack ; Peranteau, William H ; Flake, Alan W

The Journal of physiology, 2018-05-01, Vol.596 (9), p.1575-1585 [Peer Reviewed Journal]

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