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Results 1 - 10 of 1,301  for Great Falls College MSU

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1
Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention
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Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention

Bohnacker, Thomas ; Prota, Anea E ; Beaufils, Florent ; Burke, John E ; Melone, Anna ; Inglis, Alison J ; Rageot, Denise ; Sele, Alexander M ; Cmiljanovic, Vladimir ; Cmiljanovic, Natasa ; Bargsten, Katja ; Aher, Amol ; Akhmanova, Anna ; Díaz, J Fernando ; Fabbro, Doriano ; Zvelebil, Marketa ; Williams, Roger L ; Steinmetz, Michel O ; Wymann, Matthias P

Nature communications, 2017, Vol.8 (1), p.14683-14683 [Peer Reviewed Journal]

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2
Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate
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Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate

Gaugaz, Fabienne Zdenka ; Chicca, Andrea ; Redondo-Horcajo, Mariano ; Barasoain, Isabel ; Díaz, J Fernando ; Altmann, Karl-Heinz

International journal of molecular sciences, 2019-03-05, Vol.20 (5), p.1113 [Peer Reviewed Journal]

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3
A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin
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A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin

Menchon, Grégory ; Prota, Andrea E ; Lucena-Agell, Daniel ; Bucher, Pascal ; Jansen, Rolf ; Irschik, Herbert ; Müller, Rolf ; Paterson, Ian ; Díaz, J Fernando ; Altmann, Karl-Heinz ; Steinmetz, Michel O

Nature communications, 2018-05-29, Vol.9 (1), p.2106-2106 [Peer Reviewed Journal]

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4
Design and Synthesis of Pironetin Analogue/Colchicine Hybrids and Study of Their Cytotoxic Activity and Mechanisms of Interaction with Tubulin
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Design and Synthesis of Pironetin Analogue/Colchicine Hybrids and Study of Their Cytotoxic Activity and Mechanisms of Interaction with Tubulin

Vilanova, Concepción ; Díaz-Oltra, Santiago ; Murga, Juan ; Falomir, Eva ; Carda, Miguel ; Redondo-Horcajo, Mariano ; Díaz, J. Fernando ; Barasoain, Isabel ; Marco, J. Alberto

Journal of medicinal chemistry, 2014-12-26, Vol.57 (24), p.10391-10403 [Peer Reviewed Journal]

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5
High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design
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High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design

Bueno, Oskía ; Estévez Gallego, Juan ; Martins, Solange ; Prota, Andrea E ; Gago, Federico ; Gómez-SanJuan, Asier ; Camarasa, María-José ; Barasoain, Isabel ; Steinmetz, Michel O ; Díaz, J Fernando ; Pérez-Pérez, María-Jesús ; Liekens, Sandra ; Priego, Eva-María

Scientific reports, 2018-03-09, Vol.8 (1), p.4242-17 [Peer Reviewed Journal]

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6
Self-Organization of FtsZ Polymers in Solution Reveals Spacer Role of the Disordered C-Terminal Tail
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Self-Organization of FtsZ Polymers in Solution Reveals Spacer Role of the Disordered C-Terminal Tail

Huecas, Sonia ; Ramírez-Aportela, Erney ; Vergoñós, Albert ; Núñez-Ramírez, Rafael ; Llorca, Oscar ; Díaz, J. Fernando ; Juan-Rodríguez, David ; Oliva, María A ; Castellen, Patricia ; Andreu, José M

Biophysical journal, 2017-10-17, Vol.113 (8), p.1831-1844 [Peer Reviewed Journal]

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7
Synthesis, Characterization, and Application in HeLa Cells of an NIR Light Responsive Doxorubicin Delivery System Based on NaYF4:Yb,Tm@SiO2-PEG Nanoparticles
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Synthesis, Characterization, and Application in HeLa Cells of an NIR Light Responsive Doxorubicin Delivery System Based on NaYF4:Yb,Tm@SiO2-PEG Nanoparticles

Alonso-Cristobal, Paulino ; Oton-Fernandez, Olalla ; Mendez-Gonzalez, Diego ; Díaz, J Fernando ; Lopez-Cabarcos, Enrique ; Barasoain, Isabel ; Rubio-Retama, Jorge

ACS applied materials & interfaces, 2015-07-15, Vol.7 (27), p.14992-14999 [Peer Reviewed Journal]

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8
Structural model for differential cap maturation at growing microtubule ends
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Structural model for differential cap maturation at growing microtubule ends

Estévez-Gallego, Juan ; Josa-Prado, Fernando ; Ku, Siou ; Buey, Ruben M ; Balaguer, Francisco A ; Prota, Andrea E ; Lucena-Agell, Daniel ; Kamma-Lorger, Christina ; Yagi, Toshiki ; Iwamoto, Hiroyuki ; Duchesne, Laurence ; Barasoain, Isabel ; Steinmetz, Michel O ; Chrétien, Denis ; Kamimura, Shinji ; Díaz, J Fernando ; Oliva, Maria A

eLife, 2020-03-10, Vol.9, p.e50155 [Peer Reviewed Journal]

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9
Structural Basis of Noscapine Activation for Tubulin Binding
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Structural Basis of Noscapine Activation for Tubulin Binding

Oliva, María A ; Prota, Andrea E ; Rodríguez-Salarichs, Javier ; Bennani, Youssef L ; Jiménez-Barbero, Jesús ; Bargsten, Katja ; Canales, Ángeles ; Steinmetz, Michel O ; Díaz, J. Fernando

Journal of medicinal chemistry, 2020-08-13, Vol.63 (15), p.8495-8501 [Peer Reviewed Journal]

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10
Taxanes convert regions of perturbed microtubule growth into rescue sites
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Taxanes convert regions of perturbed microtubule growth into rescue sites

Rai, Ankit ; Liu, Tianyang ; Glauser, Simon ; Katrukha, Eugene A ; Estévez-Gallego, Juan ; Rodríguez-García, Ruddi ; Fang, Wei-Shuo ; Díaz, J Fernando ; Steinmetz, Michel O ; Altmann, Karl-Heinz ; Kapitein, Lukas C ; Moores, Carolyn A ; Akhmanova, Anna

Nature materials, 2020-03, Vol.19 (3), p.355-365 [Peer Reviewed Journal]

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