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Material Type: Article
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MULTIOMIC PATTERNS IN BODY FLUIDS: TECHNOLOGICAL CHALLENGE WITH A GREAT POTENTIAL TO IMPLEMENT THE ADVANCED PARADIGM OF 3P MEDICINEGerner, Christopher ; Costigliola, Vincenzo ; Golubnitschaja, OlgaMass spectrometry reviews, 2020-09, Vol.39 (5-6), p.442-451 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemiaMayer, Rupert L ; Schwarzmeier, Josef D ; Gerner, Marlene C ; Bileck, Andrea ; Mader, Johanna C ; Meier-Menches, Samuel M ; Gerner, Samuel M ; Schmetterer, Klaus G ; Pukrop, Tobias ; Reichle, Albrecht ; Slany, Astrid ; Gerner, ChristopherMolecular & cellular proteomics, 2018-02, Vol.17 (2), p.290-303 [Peer Reviewed Journal]Full text available |
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Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors: a multi-omics analysis in ovarian cancerGrunt, Thomas W ; Slany, Astrid ; Semkova, Mariya ; Colomer, Ramón ; López-Rodríguez, María Luz ; Wuczkowski, Michael ; Wagner, Renate ; Gerner, Christopher ; Stübiger, GeraldScientific reports, 2020-09-10, Vol.10 (1), p.14877-14877 [Peer Reviewed Journal]Full text available |
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Integrative Systemic and Local Metabolomics with Impact on Survival in High-Grade Serous Ovarian CancerBachmayr-Heyda, Anna ; Aust, Stefanie ; Auer, Katharina ; Meier, Samuel M ; Schmetterer, Klaus G ; Dekan, Sabine ; Gerner, Christopher ; Pils, DietmarClinical cancer research, 2017-04-15, Vol.23 (8), p.2081-2092 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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Quantification of cytokines secreted by primary human cells using multiple reaction monitoring: evaluation of analytical parametersMuqaku, Besnik ; Slany, Astrid ; Bileck, Andrea ; Kreutz, Dominique ; Gerner, ChristopherAnalytical and bioanalytical chemistry, 2015-08, Vol.407 (21), p.6525-6536 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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Multi-omics Analysis of Serum Samples Demonstrates Reprogramming of Organ Functions Via Systemic Calcium Mobilization and Platelet Activation in Metastatic MelanomaMuqaku, Besnik ; Eisinger, Martin ; Meier, Samuel M ; Tahir, Ammar ; Pukrop, Tobias ; Haferkamp, Sebastian ; Slany, Astrid ; Reichle, Albrecht ; Gerner, ChristopherMolecular & cellular proteomics, 2017-01, Vol.16 (1), p.86-99 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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An Organoruthenium Anticancer Agent Shows Unexpected Target Selectivity For PlectinMeier, Samuel M ; Kreutz, Dominique ; Winter, Lilli ; Klose, Matthias H. M ; Cseh, Klaudia ; Weiss, Tamara ; Bileck, Andrea ; Alte, Beatrix ; Mader, Johanna C ; Jana, Samir ; Chatterjee, Annesha ; Bhattacharyya, Arindam ; Hejl, Michaela ; Jakupec, Michael A ; Heffeter, Petra ; Berger, Walter ; Hartinger, Christian G ; Keppler, Bernhard K ; Wiche, Gerhard ; Gerner, ChristopherAngewandte Chemie (International ed.), 2017-07-03, Vol.56 (28), p.8267-8271 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACECavadas, Miguel ; Oikonomidi, Ioanna ; Gaspar, Catarina J ; Burbridge, Emma ; Badenes, Marina ; Félix, Inês ; Bolado, Alfonso ; Hu, Tianyi ; Bileck, Andrea ; Gerner, Christopher ; Domingos, Pedro M ; von Kriegsheim, Alex ; Adrain, ColinCell reports (Cambridge), 2017-10-17, Vol.21 (3), p.745-757 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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Peroxisome Proliferator-Activated Receptors (PPAR)γ Agonists as Master Modulators of Tumor TissueHeudobler, Daniel ; Rechenmacher, Michael ; Lüke, Florian ; Vogelhuber, Martin ; Pukrop, Tobias ; Herr, Wolfgang ; Ghibelli, Lina ; Gerner, Christopher ; Reichle, AlbrechtInternational journal of molecular sciences, 2018-11-09, Vol.19 (11), p.3540 [Peer Reviewed Journal]Full text available |
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Material Type: Article
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Sensitivity towards the GRP78 inhibitor KP1339/IT-139 is characterized by apoptosis induction via caspase 8 upon disruption of ER homeostasisSchoenhacker-Alte, Beatrix ; Mohr, Thomas ; Pirker, Christine ; Kryeziu, Kushtrim ; Kuhn, Paul-Steffen ; Buck, Alicia ; Hofmann, Thilo ; Gerner, Christopher ; Hermann, Gerrit ; Koellensperger, Gunda ; Keppler, Bernhard K ; Berger, Walter ; Heffeter, PetraCancer letters, 2017-09-28, Vol.404, p.79-88 [Peer Reviewed Journal]Full text available |