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Sarcoma Immunotherapy

R. Lor Randall ; Sunil Sharma ; Kevin B. Jones ; Launce G. Gouw

Cancers, 01 November 2011, Vol.3(4), pp.4139-4150 [Peer Reviewed Journal]

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SCF-KIT signaling induces endothelin-3 synthesis and secretion: Thereby activates and regulates endothelin-B-receptor for generating temporally- and spatially-precise nitric oxide to modulate SCF- and or KIT-expressing cell functions.

Chen, Lei L ; Zhu, Jing ; Schumacher, Jonathan ; Wei, Chongjuan ; Ramdas, Latha ; Prieto, Victor G ; Jimenez, Arnie ; Velasco, Marco A ; Tripp, Sheryl R ; Andtbacka, Robert H I ; Gouw, Launce ; Rodgers, George M ; Zhang, Liansheng ; Chan, Benjamin K ; Cassidy, Pamela B ; Benjamin, Robert S ; Leachman, Sancy A ; Frazier, Marsha L Chen, Lei L (correspondence author) ; Chen, Lei L (record owner)

PloS one, 2017, Vol.12(9), p.e0184154 [Peer Reviewed Journal]

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Investigational Aurora A kinase inhibitor alisertib (MLN8237) as an enteric-coated tablet formulation in non-hematologic malignancies: Phase 1 dose-escalation study

Falchook, Gerald ; Kurzrock, Razelle ; Gouw, Launce ; Hong, David ; McGregor, Kimberly ; Zhou, Xiaofei ; Shi, Hongliang ; Fingert, Howard ; Sharma, Sunil

Investigational New Drugs, 2014, Vol.32(6), pp.1181-1187 [Peer Reviewed Journal]

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Phase II study of amrubicin (SM-5887), a synthetic 9-aminoanthracycline, as first line treatment in patients with metastatic or unresectable soft tissue sarcoma: durable response in myxoid liposarcoma with TLS-CHOP translocation

Gupta, Sumati ; Gouw, Launce ; Wright, Jennifer ; Chawla, Sant ; Pitt, Debbie ; Wade, Mark ; Boucher, Ken ; Sharma, Sunil

Investigational New Drugs, 2016, Vol.34(2), pp.243-252 [Peer Reviewed Journal]

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Combining targeted therapy with immunotherapy (interferon-α): Rational, efficacy in gastrointestinal stromal tumor model and implications in other malignancies

Chen, Lei L ; Gouw, Launce ; Sabripour, Mahyar ; Hwu, Wen-Jen ; Benjamin, Robert S

OncoImmunology, 01 August 2012, Vol.1(5), pp.773-776

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Exploiting antitumor immunity to overcome relapse and improve remission duration

Chen, Lei ; Chen, Xinjian ; Choi, Haesun ; Sang, Hongxun ; Chen, Leo ; Zhang, Hongbo ; Gouw, Launce ; Andtbacka, Robert ; Chan, Benjamin ; Rodesch, Christopher ; Jimenez, Arnie ; Cano, Pedro ; Jones, Kimberly ; Oyedeji, Caroline ; Martins, Tom ; Hill, Harry ; Schumacher, Jonathan ; Willmore, Carlynn ; Scaife, Courtney ; Ward, John ; Morton, Kathryn ; Lor Randall, R. ; Lazar, Alexander ; Patel, Shreyaskumar ; Trent, Jonathan ; Frazier, Marsha ; Lin, Patrick ; Jensen, Peter ; Benjamin, Robert

Cancer Immunology, Immunotherapy, 2012, Vol.61(7), pp.1113-1124 [Peer Reviewed Journal]

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Proteolytic cleavage of ataxin-7 by caspase-7 modulates cellular toxicity and transcriptional dysregulation.

Young, Jessica E ; Gouw, Launce ; Propp, Stephanie ; Sopher, Bryce L ; Taylor, Jillian ; Lin, Amy ; Hermel, Evan ; Logvinova, Anna ; Chen, Sylvia F ; Chen, Shiming ; Bredesen, Dale E ; Truant, Ray ; Ptacek, Louis J ; La Spada, Albert R ; Ellerby, Lisa M Young, Jessica E (correspondence author) ; Young, Jessica E (record owner)

The Journal of biological chemistry, October 12, 2007, Vol.282(41), pp.30150-30160 [Peer Reviewed Journal]

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Retinal degeneration characterizes a spinocerebellar ataxia mapping to chromosome 3p

Launce G. Gouw ; Craig D. Kaplan ; John H. Haines ; Kathleen B. Digre ; S. Lane Rutledge ; Antoni Matilla ; Mark Leppert ; Huda Y. Zoghbi ; Louis J. Ptácek

Nature Genetics, 1995, Vol.10(1), p.89 [Peer Reviewed Journal]

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Expression of the Rho‐family GTPase gene RHOF in lymphocyte subsets and malignant lymphomas

Gouw, Launce G. ; Scott Reading, N. ; Jenson, Stephen D. ; Lim, Megan S. ; Elenitoba‐Johnson, Kojo S. J.

British Journal of Haematology, May 2005, Vol.129(4), pp.531-533 [Peer Reviewed Journal]

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