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Results 1 - 10 of 5,960  for Great Falls College MSU

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1
Targeting Mutant BRAF in Relapsed or Refractory Hairy-Cell Leukemia
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Targeting Mutant BRAF in Relapsed or Refractory Hairy-Cell Leukemia

Tiacci, Enrico ; Park, Jae H ; De Carolis, Luca ; Chung, Stephen S ; Broccoli, Alessandro ; Scott, Sasinya ; Zaja, Francesco ; Devlin, Sean ; Pulsoni, Alessandro ; Chung, Young R ; Cimminiello, Michele ; Kim, Eunhee ; Rossi, Davide ; Stone, Richard M ; Motta, Giovanna ; Saven, Alan ; Varettoni, Marzia ; Altman, Jessica K ; Anastasia, Antonella ; Grever, Michael R ; Ambrosetti, Achille ; Rai, Kanti R ; Fraticelli, Vincenzo ; Lacouture, Mario E ; Carella, Angelo M ; Levine, Ross L ; Leoni, Pietro ; Rambaldi, Alessandro ; Falzetti, Franca ; Ascani, Stefano ; Capponi, Monia ; Martelli, Maria P ; Park, Christopher Y ; Pileri, Stefano A ; Rosen, Neal ; Foà, Robin ; Berger, Michael F ; Zinzani, Pier L ; Abdel-Wahab, Omar ; Falini, Brunangelo ; Tallman, Martin S

The New England journal of medicine, 2015-10-29, Vol.373 (18), p.1733-1747 [Peer Reviewed Journal]

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2
RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth
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RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

Hatzivassiliou, Georgia ; Song, Kyung ; Yen, Ivana ; Brandhuber, Barbara J ; Anderson, Daniel J ; Alvarado, Ryan ; Ludlam, Mary J. C ; Stokoe, David ; Gloor, Susan L ; Vigers, Guy ; Morales, Tony ; Aliagas, Ignacio ; Liu, Bonnie ; Sideris, Steve ; Hoeflich, Klaus P ; Jaiswal, Bijay S ; Seshagiri, Somasekar ; Koeppen, Hartmut ; Belvin, Marcia ; Friedman, Lori S ; Malek, Shiva

Nature (London), 2010-02-03, Vol.464 (7287), p.431-435 [Peer Reviewed Journal]

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3
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
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COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

Johannessen, Cory M ; Boehm, Jesse S ; Kim, So Young ; Thomas, Sapana R ; Wardwell, Leslie ; Johnson, Laura A ; Emery, Caroline M ; Stransky, Nicolas ; Cogdill, Alexandria P ; Barretina, Jordi ; Caponigro, Giordano ; Hieronymus, Haley ; Murray, Ryan R ; Salehi-Ashtiani, Kourosh ; Hill, David E ; Vidal, Marc ; Zhao, Jean J ; Yang, Xiaoping ; Alkan, Ozan ; Kim, Sungjoon ; Harris, Jennifer L ; Wilson, Christopher J ; Myer, Vic E ; Finan, Peter M ; Root, David E ; Roberts, Thomas M ; Golub, Todd ; Flaherty, Keith T ; Dummer, Reinhard ; Weber, Barbara L ; Sellers, William R ; Schlegel, Robert ; Wargo, Jennifer A ; Hahn, William C ; Garraway, Levi A

Nature (London), 2010-11-24, Vol.468 (7326), p.968-972 [Peer Reviewed Journal]

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4
Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR
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Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR

Prahallad, Anirudh ; Sun, Chong ; Huang, Sidong ; Di Nicolantonio, Federica ; Salazar, Ramon ; Zecchin, Davide ; Beijersbergen, Roderick L ; Bardelli, Alberto ; Bernards, René

Nature (London), 2012-01-26, Vol.483 (7387), p.100-103 [Peer Reviewed Journal]

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5
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

Poulikakos, Poulikos I ; Persaud, Yogindra ; Janakiraman, Manickam ; Kong, Xiangju ; Ng, Charles ; Moriceau, Gatien ; Shi, Hubing ; Atefi, Mohammad ; Titz, Bjoern ; Gabay, May Tal ; Salton, Maayan ; Dahlman, Kimberly B ; Tadi, Madhavi ; Wargo, Jennifer A ; Flaherty, Keith T ; Kelley, Mark C ; Misteli, Tom ; Chapman, Paul B ; Sosman, Jeffrey A ; Graeber, Thomas G ; Ribas, Antoni ; Lo, Roger S ; Rosen, Neal ; Solit, David B

Nature (London), 2011-11-23, Vol.480 (7377), p.387-390 [Peer Reviewed Journal]

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6
Heterogeneity of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer and potential effects on therapy in the CAPRI GOIM trial
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Heterogeneity of KRAS, NRAS, BRAF and PIK3CA mutations in metastatic colorectal cancer and potential effects on therapy in the CAPRI GOIM trial

Normanno, N ; Rachiglio, A.M ; Lambiase, M ; Martinelli, E ; Fenizia, F ; Esposito, C ; Roma, C ; Troiani, T ; Rizzi, D ; Tatangelo, F ; Botti, G ; Maiello, E ; Colucci, G ; Ciardiello, F ; Giuliani, F ; Simone, G ; Febbraro, A ; Tommaselli, E ; Cinieri, S ; Criscuolo, M ; Perrino, A ; Rinaldi, A ; Bordonaro, R ; Manusia, M ; Romito, S ; Bufo, P ; Cartenì, G ; Biglietto, M ; Nappi, O ; Cardarelli, A ; Montesarchio, E ; Micheli, P ; Nasti, G ; Chicchinelli, N ; Iannaccone, A ; Russo, A ; Cabibi, D ; Giaccone, P ; Barone, C ; Rindi, G ; Tonini, G ; Onetti Muda, A ; Perrone, G ; Latiano, T ; Graziano, P ; Pisconti, S ; Sebastio, A

Annals of oncology, 2015-08, Vol.26 (8), p.1710-1714 [Peer Reviewed Journal]

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7
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

Nazarian, Ramin ; Shi, Hubing ; Wang, Qi ; Kong, Xiangju ; Koya, Richard C ; Lee, Hane ; Chen, Zugen ; Lee, Mi-Kyung ; Attar, Narsis ; Sazegar, Hooman ; Chodon, Thinle ; Nelson, Stanley F ; McArthur, Grant ; Sosman, Jeffrey A ; Ribas, Antoni ; Lo, Roger S

Nature (London), 2010-11-24, Vol.468 (7326), p.973-977 [Peer Reviewed Journal]

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8
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
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Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

Bollag, Gideon ; Hirth, Peter ; Tsai, James ; Zhang, Jiazhong ; Ibrahim, Prabha N ; Cho, Hanna ; Spevak, Wayne ; Zhang, Chao ; Zhang, Ying ; Habets, Gaston ; Burton, Elizabeth A ; Wong, Bernice ; Tsang, Garson ; West, Brian L ; Powell, Ben ; Shellooe, Rafe ; Marimuthu, Adhirai ; Nguyen, Hoa ; Zhang, Kam Y. J ; Artis, Dean R ; Schlessinger, Joseph ; Su, Fei ; Higgins, Brian ; Iyer, Raman ; D’Andrea, Kurt ; Koehler, Astrid ; Stumm, Michael ; Lin, Paul S ; Lee, Richard J ; Grippo, Joseph ; Puzanov, Igor ; Kim, Kevin B ; Ribas, Antoni ; McArthur, Grant A ; Sosman, Jeffrey A ; Chapman, Paul B ; Flaherty, Keith T ; Xu, Xiaowei ; Nathanson, Katherine L ; Nolop, Keith

Nature (London), 2010-09-07, Vol.467 (7315), p.596-599 [Peer Reviewed Journal]

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9
Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma
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Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma

Sun, Chong ; Wang, Liqin ; Huang, Sidong ; Heynen, Guus J. J. E ; Prahallad, Anirudh ; Robert, Caroline ; Haanen, John ; Blank, Christian ; Wesseling, Jelle ; Willems, Stefan M ; Zecchin, Davide ; Hobor, Sebastijan ; Bajpe, Prashanth K ; Lieftink, Cor ; Mateus, Christina ; Vagner, Stephan ; Grernrum, Wipawadee ; Hofland, Ingrid ; Schlicker, Andreas ; Wessels, Lodewyk F. A ; Beijersbergen, Roderick L ; Bardelli, Alberto ; Di Nicolantonio, Federica ; Eggermont, Alexander M. M ; Bernards, Rene

Nature (London), 2014-03-26, Vol.508 (7494), p.118-122 [Peer Reviewed Journal]

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10
Suppression of BRAF/MEK/MAP Kinase Pathway Restores Expression of Iodide-Metabolizing Genes in Thyroid Cells Expressing the V600E BRAF Mutant
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Suppression of BRAF/MEK/MAP Kinase Pathway Restores Expression of Iodide-Metabolizing Genes in Thyroid Cells Expressing the V600E BRAF Mutant

Dingxie Liu ; Shuiying Hu ; Peng Hou ; David Jiang ; Stephen Condouris ; Mingzhao Xing

Clinical Cancer Research, 2007-02-15, Vol.13 (4), p.1341-1349 [Peer Reviewed Journal]

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