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Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate.

Zhang, Zhihong ; Smart, Tristan J ; Choi, Hwanho ; Hardy, Florence ; Lohans, Christopher T ; Abboud, Martine I ; Richardson, Melodie S W ; Paton, Robert S ; Mcdonough, Michael A ; Schofield, Christopher J Zhang, Zhihong (correspondence author) ; Zhang, Zhihong (record owner)

Proceedings of the National Academy of Sciences of the United States of America, May 2, 2017, Vol.114(18), pp.4667-4672 [Peer Reviewed Journal]

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Reporter Ligand NMR Screening Method for 2‑Oxoglutarate Oxygenase Inhibitors

Leung, Ivanhoe K. H ; Demetriades, Marina ; Hardy, Adam P ; Lejeune, Clarisse ; Smart, Tristan J ; Szöllössi, Andrea ; Kawamura, Akane ; Schofield, Christopher J ; Claridge, Timothy D. W

Journal of Medicinal Chemistry, 24 January 2013, Vol.56(2), pp.547-555 [Peer Reviewed Journal]

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3
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Is JmjC Oxygenase Catalysis Limited to Demethylation?

Hopkinson, Richard J. ; Walport, Louise J. ; Münzel, Martin ; Rose, Nathan R. ; Smart, Tristan J. ; Kawamura, Akane ; Claridge, Timothy D. W. ; Schofield, Christopher J.

Angewandte Chemie International Edition, 22 July 2013, Vol.52(30), pp.7709-7713 [Peer Reviewed Journal]

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4
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Studies on the Glutathione-Dependent Formaldehyde-Activating Enzyme from Paracoccus denitrificans

Richard J Hopkinson ; Ivanhoe K H Leung ; Tristan J Smart ; Nathan R Rose ; Luc Henry ; Timothy D W Claridge ; Christopher J Schofield

PLoS ONE, 01 January 2015, Vol.10(12), p.e0145085 [Peer Reviewed Journal]

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5
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Lysine‐241 Has a Role in Coupling 2OG Turnover with Substrate Oxidation During KDM4‐Catalysed Histone Demethylation

Hancock, Rebecca L. ; Abboud, Martine I. ; Smart, Tristan J. ; Flashman, Emily ; Kawamura, Akane ; Schofield, Christopher J. ; Hopkinson, Richard J.

ChemBioChem, 04 May 2018, Vol.19(9), pp.917-921 [Peer Reviewed Journal]

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6
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Is JmjC Oxygenase Catalysis Limited to Demethylation?

Hopkinson, Richard J. ; Walport, Louise J. ; Münzel, Martin ; Rose, Nathan R. ; Smart, Tristan J. ; Kawamura, Akane ; Claridge, Timothy D. W. ; Schofield, Christopher J.

Angewandte Chemie, 22 July 2013, Vol.125(30), pp.7863-7867 [Peer Reviewed Journal]

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Studies on the selectivity of proline hydroxylases reveal new substrates including bicycles

Smart, Tristan J ; Hamed, Refaat B ; Claridge, Timothy D.W ; Schofield, Christopher J

Bioorganic Chemistry, January 2020, Vol.94 [Peer Reviewed Journal]

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British Society for Gene Therapy 2012March 9, 2012UCL Institute of Child Health, London

Cheng, Seng H ; Smart, Nicola ; Cartier, Nathalie ; Pizzitola, I ; Anjos-Afonso, F ; Marin, V ; Lassailly, F ; Finney, H ; Pule, M ; Biondi, A ; Biagi, E ; Bonnet, D ; Carmo, Marlene ; Arumugam, Paritha ; Montiel-Equihua, Claudia A ; Alonso-Ferrero, Maria E ; Schambach, Axel ; Baum, Christopher ; Risma, Kimberly ; Malik, Punam ; Thrasher, Adrian J ; Jordan, Michael B ; Gaspar, Bobby ; Gicquel, Evelyne ; Charton, Karine ; Daniele, Nathalie ; Richard, Isabelle ; Bendle, Gavin M ; Linnemann, Carsten ; Bies, Laura ; Song, Ji-Ying ; Schumacher, Ton N ; Singh, Charanjit ; Munkonge, Felix M ; Smith, Stephen N ; Griesenbach, Uta ; Carzaniga, Raffaella ; Pape, Tillmann ; Cheng, Seng H ; Rogers, Andrew ; Dewar, Ann ; Alton, Eric W F W ; Sung, Peggy ; Mukherjee, Sayandip ; Thrasher, Adrian J ; Gubernator, Miriam ; Riu, Federica ; Mitchell, Kathryn ; Katare, Rajesh ; Spinetti, Gaia ; Prandi, Francesca ; Pesce, Maurizio ; Madeddu, Paolo ; Ruffert, Karelia ; Fourcade, Stéphane ; Ferrer, Isidre ; Portero-Otin, Manuel ; L'Homme, Bruno ; Bièche, Ivan ; Laurendeau, Ingrid ; Ahouansou, Ornella ; Fouquet, Françoise ; Guidoux-Boralévi, Sylvie ; Aubourg, Patrick ; Pujol, Aurora ; Cartier, Nathalie ; Ghorashian, Sara ; Holler, Angelika ; Flutter, Barry ; Xue, Shao-An ; Fallah-Arani, Farnaz ; Sivakumaran, Janani ; Bennett, Clare ; Morris, Emma ; Stauss, Hans J ; Chakraverty, Ronjon ; Mitchell, Kathryn J ; Katare, Rajesh ; Riu, Federica ; Gubernator, Miriam ; Beltrami, Antonio P ; Madeddu, Paolo ; Popplewell, Linda ; Koo, Taeyoung ; Kymäläinen, Hanna ; Leclerc, Xavier ; Duclert, Aymeric ; Mouly, Vincent ; Voit, Thomas ; Paques, Frédéric ; Cedrone, Frederic ; Yáñez-Muñoz, Rafael J ; Dickson, George ; Pallant, Celeste ; Cathomen, Toni ; Dannemann, Nadine ; Qasim, Wasim ; Naldini, Luigi ; Kinnon, Christine ; Howe, Steven ; Thrasher, Adrian ; Vandermeulen, Gaëlle ; Athanasopoulos, Takis ; Trundley, Anita ; Foster, Keith ; Preat, Véronique ; Yáñez-Muñoz, Rafael J ; Dickson, George ; Mukherjee, Sayandip ; Pipino, Caterina ; Sung, Peggy ; Decoppi, Paolo ; Thrasher, Adrian ; Rivat, Christine ; Booth, Claire ; Blundell, Michael ; Thrasher, Adrian J ; Gaspar, Hubert B ; Carr, Bob ; Siupa, Agnieszka ; Hole, Patrick ; Malloy, Andrew ; Hannell, Claire ; Georgiadis, C ; Semenova, K ; Mcgrath, J ; Di, W ; Qasim, W ; Zhang, Fang ; Knight, Sean ; Collins, Mary ; Takeuchi, Yasuhiro ; Antoniou, Michael ; Thrasher, Adrian J ; Boza, Maria G ; Wanisch, Klaus ; Tizzano, Eduardo ; Yáñez-Muñoz, Rafael J ; Sanchez, Noëlia ; Lao, Nga ; Gallagher, Clair ; Aherne, Sinead ; Doolan, Padraig ; Clarke, Colin ; Clynes, Martin ; Barron, Niall ; Lu-Nguyen, Ngoc B ; Broadstock, Martin ; Yáñez-Muñoz, Rafael J ; Field, Anne-Christine ; Stauss, Hans J ; Morris, Emma C ; Qasim, Waseem ; Munye, Mustafa M ; Howe, Steven J ; Hart, Stephen L ; Montiel-Equihua, Claudia A ; Zhang, Lin ; Knight, Sean ; Saadeh, Heba ; Scholz, Simone ; Carmo, Marlene ; Alonso-Ferrero, Maria E ; Blundell, Michael P ; Monkeviciute, Aiste ; Schulz, Reiner ; Collins, Mary ; Takeuchi, Yasuhiro ; Schmidt, Manfred ; Fairbanks, Lynette ; Antoniou, Michael ; Thrasher, Adrian J ; Gaspar, H Bobby ; Delhove, Juliette M K M ; Waddington, Simon N ; Ward, Natalie J ; Jathoul, Amit P ; Pule, Martin A ; Mckay, Tristan R ; Buckley, Suzanne M K ; Hutchinson, Lauren ; Boza-Morán, Maria Gabriela ; Yáñez-Muñoz, Rafael J ; Griesenbach, Uta ; Mclachlan, Gerry ; Collie, David D ; Innes, J Alastair ; Higgins, Tracy E ; Cheng, Seng H ; Scheule, Ronald K ; Alton, Eric W F W ; Davies, Jane C ; Hyde, Steve C ; Gill, Deborah R ; Porteous, David J ; Boyd, A Christopher ; Sergijenko, Ana ; Langford-Smith, Alexander ; Langford-Smith, Kia J ; Wynn, Robert F ; Jarmin, Susan ; Foster, Helen ; Trollet, Capucine ; Dickson, George ; Foster, Keith ; Vink, Conrad A ; Howe, Steven J ; Steichen, Clara ; Corbineau, Sébastien ; Pucéat, Michel ; Weber, Anne ; Dubart-Kupperschmitt, Anne ; Alonso-Ferrero, Maria E ; Bartolovic, Kerol ; Kinnon, Christine ; Mata, Marcia ; Til, Niek P Van ; Howe, Steven J ; Alonso-Ferrero, Maria E ; Langford-Smith, Alexander ; Burke, Derek ; Heales, Simon ; Bigger, Brian W ; Thrasher, Adrian ; Gaspar, Bobby ; Vandermeulen, Gaëlle ; Uyttenhove, Catherine ; de Plaen, Etienne ; van Den Eynde, Benoît ; Preat, Véronique ; Grimshaw, Benjamin D ; Pule, Martin A ; Linch, David C ; Ingrao, Dina D I ; Galy, Anne A G ; Fenard, David D F ; Aitchison, Katherine L ; Rahim, Ahad A ; Hughes, Derralynn ; Kinnon, Christine ; Waddington, Simon N ; Howe, Steven J ; Locanto, Elisabetta ; Hitchman, Richard B ; King, Linda A ; Chan, Lucas ; Ma, Yu-Qian ; Krishnamurthy, Pramila ; Darling, David ; Giunti, Giulia

Human Gene Therapy, 01 May 2012, Vol.23(5), pp.A1-A22 [Peer Reviewed Journal]

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